Compile Data Set for Download or QSAR

Found 32 hits Enz. Inhib. hit(s) with all data for entry = 50006057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496611 (CHEMBL3134416) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1cc(O)c(C(O)=O)c(CCCCC)c1 Show InChI InChI=1S/C24H30O7/c1-3-5-7-9-15-11-17(25)13-19(26)22(15)24(30)31-18-12-16(10-8-6-4-2)21(23(28)29)20(27)14-18/h11-14,25-27H,3-10H2,1-2H3,(H,28,29)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496611 (CHEMBL3134416) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1cc(O)c(C(O)=O)c(CCCCC)c1 Show InChI InChI=1S/C24H30O7/c1-3-5-7-9-15-11-17(25)13-19(26)22(15)24(30)31-18-12-16(10-8-6-4-2)21(23(28)29)20(27)14-18/h11-14,25-27H,3-10H2,1-2H3,(H,28,29)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496611 (CHEMBL3134416) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1cc(O)c(C(O)=O)c(CCCCC)c1 Show InChI InChI=1S/C24H30O7/c1-3-5-7-9-15-11-17(25)13-19(26)22(15)24(30)31-18-12-16(10-8-6-4-2)21(23(28)29)20(27)14-18/h11-14,25-27H,3-10H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496611 (CHEMBL3134416) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1cc(O)c(C(O)=O)c(CCCCC)c1 Show InChI InChI=1S/C24H30O7/c1-3-5-7-9-15-11-17(25)13-19(26)22(15)24(30)31-18-12-16(10-8-6-4-2)21(23(28)29)20(27)14-18/h11-14,25-27H,3-10H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496604 (CHEMBL3134406) Show SMILES OC(=O)c1cc(ccc1O)\N=N\c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C13H9N3O5/c17-12-5-4-9(7-11(12)13(18)19)15-14-8-2-1-3-10(6-8)16(20)21/h1-7,17H,(H,18,19)/b15-14+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496617 (CHEMBL3134419) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C19H20O7/c1-2-3-4-5-11-8-12(20)9-16(22)17(11)19(25)26-13-6-7-14(18(23)24)15(21)10-13/h6-10,20-22H,2-5H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496622 (CHEBI:34640 | CHEMBL1739417) Show SMILES Nc1ccc(\N=N\c2ccccc2)c(N)c1 Show InChI InChI=1S/C12H12N4/c13-9-6-7-12(11(14)8-9)16-15-10-4-2-1-3-5-10/h1-8H,13-14H2/b16-15+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496612 (CHEMBL3134410) Show SMILES COc1ccc(\C=C(/C#N)c2ccc(cc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C16H12N2O3/c1-21-16-8-2-12(3-9-16)10-14(11-17)13-4-6-15(7-5-13)18(19)20/h2-10H,1H3/b14-10+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50052414 (4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthale...) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50061625 (4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...) Show SMILES CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(cc3)C(O)=O)ccc12 Show InChI InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496607 (CHEMBL3134407) Show SMILES CCCCCCCCCC(=O)N\N=C\c1ccc(OC(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C24H29BrN2O3/c1-2-3-4-5-6-7-8-12-23(28)27-26-18-19-13-15-22(16-14-19)30-24(29)20-10-9-11-21(25)17-20/h9-11,13-18H,2-8,12H2,1H3,(H,27,28)/b26-18+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496606 (CHEMBL3134409) Show SMILES Cc1ccc(C)c(\C=C\c2cc(C)ccc2C)c1 Show InChI InChI=1S/C18H20/c1-13-5-7-15(3)17(11-13)9-10-18-12-14(2)6-8-16(18)4/h5-12H,1-4H3/b10-9+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496605 (CHEMBL3134411) Show SMILES OC(=O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C14H12O3/c15-14(16)12-6-8-13(9-7-12)17-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,15,16)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496621 (CHEMBL3134405) Show SMILES [O-][N+](=O)c1cccc(NC(=O)c2ccc(cc2Cl)[N+]([O-])=O)c1 Show InChI InChI=1S/C13H8ClN3O5/c14-12-7-10(17(21)22)4-5-11(12)13(18)15-8-2-1-3-9(6-8)16(19)20/h1-7H,(H,15,18)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496620 (CHEMBL3134413) Show SMILES OC(=O)c1ccc(NCc2cc(Cl)cc(Cl)c2O)cc1O Show InChI InChI=1S/C14H11Cl2NO4/c15-8-3-7(13(19)11(16)4-8)6-17-9-1-2-10(14(20)21)12(18)5-9/h1-5,17-19H,6H2,(H,20,21)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496619 (CHEMBL3134412) Show SMILES CCOc1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C9H10O4/c1-2-13-6-3-4-7(9(11)12)8(10)5-6/h3-5,10H,2H2,1H3,(H,11,12)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496609 (CHEMBL3134418) Show SMILES CCCCCc1cc(OC(=O)c2ccc(O)cc2O)cc(O)c1C(O)=O Show InChI InChI=1S/C19H20O7/c1-2-3-4-5-11-8-13(10-16(22)17(11)18(23)24)26-19(25)14-7-6-12(20)9-15(14)21/h6-10,20-22H,2-5H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496618 (CHEMBL3134408) Show SMILES CC(C)(C)CC(C)(C)c1ccc(OC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C21H26O2/c1-20(2,3)15-21(4,5)17-11-13-18(14-12-17)23-19(22)16-9-7-6-8-10-16/h6-14H,15H2,1-5H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496617 (CHEMBL3134419) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C19H20O7/c1-2-3-4-5-11-8-12(20)9-16(22)17(11)19(25)26-13-6-7-14(18(23)24)15(21)10-13/h6-10,20-22H,2-5H2,1H3,(H,23,24)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496614 (CHEMBL3134421) Show SMILES CCCCCc1cc(O)cc(OC(=O)c2c(O)cc(O)cc2CCCCC)c1 Show InChI InChI=1S/C23H30O5/c1-3-5-7-9-16-11-18(24)14-20(12-16)28-23(27)22-17(10-8-6-4-2)13-19(25)15-21(22)26/h11-15,24-26H,3-10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496614 (CHEMBL3134421) Show SMILES CCCCCc1cc(O)cc(OC(=O)c2c(O)cc(O)cc2CCCCC)c1 Show InChI InChI=1S/C23H30O5/c1-3-5-7-9-16-11-18(24)14-20(12-16)28-23(27)22-17(10-8-6-4-2)13-19(25)15-21(22)26/h11-15,24-26H,3-10H2,1-2H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496613 (CHEMBL3134404) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1cc(CCCCC)c2C(=O)OC(C)(C)Oc2c1 Show InChI InChI=1S/C27H34O7/c1-5-7-9-11-17-13-19(28)15-21(29)23(17)25(30)32-20-14-18(12-10-8-6-2)24-22(16-20)33-27(3,4)34-26(24)31/h13-16,28-29H,5-12H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496609 (CHEMBL3134418) Show SMILES CCCCCc1cc(OC(=O)c2ccc(O)cc2O)cc(O)c1C(O)=O Show InChI InChI=1S/C19H20O7/c1-2-3-4-5-11-8-13(10-16(22)17(11)18(23)24)26-19(25)14-7-6-12(20)9-15(14)21/h6-10,20-22H,2-5H2,1H3,(H,23,24)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496610 (CHEMBL3134420) Show SMILES OC(=O)c1ccc(OC(=O)c2ccc(O)cc2O)cc1O Show InChI InChI=1S/C14H10O7/c15-7-1-3-10(11(16)5-7)14(20)21-8-2-4-9(13(18)19)12(17)6-8/h1-6,15-17H,(H,18,19)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496616 (CHEMBL3134415) Show SMILES CCCCCc1cc(OC(=O)c2c(CCCCC)cc(OCc3ccccc3)cc2OCc2ccccc2)cc(O)c1C(=O)OCc1ccccc1 Show InChI InChI=1S/C45H48O7/c1-3-5-10-24-36-27-39(28-40(46)42(36)44(47)51-32-35-22-16-9-17-23-35)52-45(48)43-37(25-11-6-4-2)26-38(49-30-33-18-12-7-13-19-33)29-41(43)50-31-34-20-14-8-15-21-34/h7-9,12-23,26-29,46H,3-6,10-11,24-25,30-32H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496615 (CHEMBL3134417) Show SMILES Oc1cc(OC(=O)c2ccc(OCc3ccccc3)cc2OCc2ccccc2)ccc1C(=O)OCc1ccccc1 Show InChI InChI=1S/C35H28O7/c36-32-20-29(17-18-30(32)34(37)41-24-27-14-8-3-9-15-27)42-35(38)31-19-16-28(39-22-25-10-4-1-5-11-25)21-33(31)40-23-26-12-6-2-7-13-26/h1-21,36H,22-24H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496613 (CHEMBL3134404) Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1cc(CCCCC)c2C(=O)OC(C)(C)Oc2c1 Show InChI InChI=1S/C27H34O7/c1-5-7-9-11-17-13-19(28)15-21(29)23(17)25(30)32-20-14-18(12-10-8-6-2)24-22(16-20)33-27(3,4)34-26(24)31/h13-16,28-29H,5-12H2,1-4H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496610 (CHEMBL3134420) Show SMILES OC(=O)c1ccc(OC(=O)c2ccc(O)cc2O)cc1O Show InChI InChI=1S/C14H10O7/c15-7-1-3-10(11(16)5-7)14(20)21-8-2-4-9(13(18)19)12(17)6-8/h1-6,15-17H,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496608 (CHEBI:66955 | CHEMBL3134414) Show SMILES CCCCCc1cc(O)cc(O)c1C(O)=O Show InChI InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496616 (CHEMBL3134415) Show SMILES CCCCCc1cc(OC(=O)c2c(CCCCC)cc(OCc3ccccc3)cc2OCc2ccccc2)cc(O)c1C(=O)OCc1ccccc1 Show InChI InChI=1S/C45H48O7/c1-3-5-10-24-36-27-39(28-40(46)42(36)44(47)51-32-35-22-16-9-17-23-35)52-45(48)43-37(25-11-6-4-2)26-38(49-30-33-18-12-7-13-19-33)29-41(43)50-31-34-20-14-8-15-21-34/h7-9,12-23,26-29,46H,3-6,10-11,24-25,30-32H2,1-2H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50496608 (CHEBI:66955 | CHEMBL3134414) Show SMILES CCCCCc1cc(O)cc(O)c1C(O)=O Show InChI InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Yersinia pestis)	BDBM50496615 (CHEMBL3134417) Show SMILES Oc1cc(OC(=O)c2ccc(OCc3ccccc3)cc2OCc2ccccc2)ccc1C(=O)OCc1ccccc1 Show InChI InChI=1S/C35H28O7/c36-32-20-29(17-18-30(32)34(37)41-24-27-14-8-3-9-15-27)42-35(38)31-19-16-28(39-22-25-10-4-1-5-11-25)21-33(31)40-23-26-12-6-2-7-13-26/h1-21,36H,22-24H2	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Hawai'i at Hilo Curated by ChEMBL					Assay Description Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis				Medchemcomm 4: (2013) Article DOI: 10.1039/C3MD00238A BindingDB Entry DOI: 10.7270/Q23F4SM4
					More data for this Ligand-Target Pair