Compile Data Set for Download or QSAR

Found 19 hits Enz. Inhib. hit(s) with all data for entry = 50008430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519299 (CHEMBL4536230) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3ccn(CC4CCN(CC4)C4CCCCC=C4)c3)c2n1 |c:33| Show InChI InChI=1S/C27H36N8O/c1-19-30-25(28)24-26(31-19)35(18-29-24)23-16-34(17-23)27(36)21-10-11-32(15-21)14-20-8-12-33(13-9-20)22-6-4-2-3-5-7-22/h4,6,10-11,15,18,20,22-23H,2-3,5,7-9,12-14,16-17H2,1H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519299 (CHEMBL4536230) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3ccn(CC4CCN(CC4)C4CCCCC=C4)c3)c2n1 |c:33| Show InChI InChI=1S/C27H36N8O/c1-19-30-25(28)24-26(31-19)35(18-29-24)23-16-34(17-23)27(36)21-10-11-32(15-21)14-20-8-12-33(13-9-20)22-6-4-2-3-5-7-22/h4,6,10-11,15,18,20,22-23H,2-3,5,7-9,12-14,16-17H2,1H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519305 (CHEMBL4449427) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3ccn(CC4CCN(CC4)C4CCCCCC4)c3)c2n1 Show InChI InChI=1S/C27H38N8O/c1-19-30-25(28)24-26(31-19)35(18-29-24)23-16-34(17-23)27(36)21-10-11-32(15-21)14-20-8-12-33(13-9-20)22-6-4-2-3-5-7-22/h10-11,15,18,20,22-23H,2-9,12-14,16-17H2,1H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519303 (CHEMBL4590955) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3cc(CC4CCN(CC4)C4CCCCCC4)n(C)n3)c2n1 Show InChI InChI=1S/C27H39N9O/c1-18-30-25(28)24-26(31-18)36(17-29-24)22-15-35(16-22)27(37)23-14-21(33(2)32-23)13-19-9-11-34(12-10-19)20-7-5-3-4-6-8-20/h14,17,19-20,22H,3-13,15-16H2,1-2H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519301 (CHEMBL4439045) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3cc(CN4CCN(CC4)C4CCCCCC4)n(C)n3)c2n1 Show InChI InChI=1S/C26H38N10O/c1-18-29-24(27)23-25(30-18)36(17-28-23)21-15-35(16-21)26(37)22-13-20(32(2)31-22)14-33-9-11-34(12-10-33)19-7-5-3-4-6-8-19/h13,17,19,21H,3-12,14-16H2,1-2H3,(H2,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519302 (CHEMBL4553357) Show SMILES Cc1nc(N)c2ncn(c2n1)C1(C)CN(C1)C(=O)c1cc(CN2CCN(CC2)C2CCCCCC2)n(C)n1 Show InChI InChI=1S/C27H40N10O/c1-19-30-24(28)23-25(31-19)37(18-29-23)27(2)16-36(17-27)26(38)22-14-21(33(3)32-22)15-34-10-12-35(13-11-34)20-8-6-4-5-7-9-20/h14,18,20H,4-13,15-17H2,1-3H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519304 (CHEMBL4440677) Show SMILES CC(C)N1CCN(Cc2cc(nn2C)C(=O)N2CC(C2)n2cnc3c(N)ncnc23)CC1 Show InChI InChI=1S/C21H30N10O/c1-14(2)29-6-4-28(5-7-29)9-15-8-17(26-27(15)3)21(32)30-10-16(11-30)31-13-25-18-19(22)23-12-24-20(18)31/h8,12-14,16H,4-7,9-11H2,1-3H3,(H2,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of V5-tagged SMYD2 (unknown origin) transfected in HEK293 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methylati...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human U2OS cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human MCF7 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human HeLa cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 methy...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human CAL120 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53 met...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519300 (CHEMBL4520134) Show SMILES Cc1cc2n(cnc2c(N)n1)C1(C)CN(C1)C(=O)c1ccn(CC2CCN(CC2)[C@@H]2CCCCC=C2)c1 |r,c:38| Show InChI InChI=1S/C29H39N7O/c1-21-15-25-26(27(30)32-21)31-20-36(25)29(2)18-35(19-29)28(37)23-11-12-33(17-23)16-22-9-13-34(14-10-22)24-7-5-3-4-6-8-24/h5,7,11-12,15,17,20,22,24H,3-4,6,8-10,13-14,16,18-19H2,1-2H3,(H2,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of V5-tagged SMYD2 (unknown origin) transfected in human MDA-MB-231 cells co-transfected with FLAG-tagged p53 assessed as reduction in p53...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519302 (CHEMBL4553357) Show SMILES Cc1nc(N)c2ncn(c2n1)C1(C)CN(C1)C(=O)c1cc(CN2CCN(CC2)C2CCCCCC2)n(C)n1 Show InChI InChI=1S/C27H40N10O/c1-19-30-24(28)23-25(31-19)37(18-29-23)27(2)16-36(17-27)26(38)22-14-21(33(3)32-22)15-34-10-12-35(13-11-34)20-8-6-4-5-7-9-20/h14,18,20H,4-13,15-17H2,1-3H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519303 (CHEMBL4590955) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3cc(CC4CCN(CC4)C4CCCCCC4)n(C)n3)c2n1 Show InChI InChI=1S/C27H39N9O/c1-18-30-25(28)24-26(31-18)36(17-29-24)22-15-35(16-22)27(37)23-14-21(33(2)32-23)13-19-9-11-34(12-10-19)20-7-5-3-4-6-8-20/h14,17,19-20,22H,3-13,15-16H2,1-2H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519305 (CHEMBL4449427) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3ccn(CC4CCN(CC4)C4CCCCCC4)c3)c2n1 Show InChI InChI=1S/C27H38N8O/c1-19-30-25(28)24-26(31-19)35(18-29-24)23-16-34(17-23)27(36)21-10-11-32(15-21)14-20-8-12-33(13-9-20)22-6-4-2-3-5-7-22/h10-11,15,18,20,22-23H,2-9,12-14,16-17H2,1H3,(H2,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50519301 (CHEMBL4439045) Show SMILES Cc1nc(N)c2ncn(C3CN(C3)C(=O)c3cc(CN4CCN(CC4)C4CCCCCC4)n(C)n3)c2n1 Show InChI InChI=1S/C26H38N10O/c1-18-29-24(27)23-25(30-18)36(17-28-23)21-15-35(16-21)26(37)22-13-20(32(2)31-22)14-33-9-11-34(12-10-33)19-7-5-3-4-6-8-19/h13,17,19,21H,3-12,14-16H2,1-2H3,(H2,27,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human SMYD2 (1 to 433 residues) expressed in baculovirus infected Sf9 insect cells using biotinylated-p53 peptide (361 to 3...				J Med Chem 62: 7669-7683 (2019) Article DOI: 10.1021/acs.jmedchem.9b00112 BindingDB Entry DOI: 10.7270/Q2R78JK4
					More data for this Ligand-Target Pair				3D Structure (crystal)