Found 114 hits Enz. Inhib. hit(s) with all data for entry = 50008790 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066614
![PNG](/data/jpeg/tenK5006/BindingDB_50066614.png) ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...)Show SMILES NC(=N)c1ccc(\C=C2/CCCC\C(=C/c3ccc(cc3)C(N)=N)C2=O)cc1 Show InChI InChI=1S/C23H24N4O/c24-22(25)17-9-5-15(6-10-17)13-19-3-1-2-4-20(21(19)28)14-16-7-11-18(12-8-16)23(26)27/h5-14H,1-4H2,(H3,24,25)(H3,26,27)/b19-13+,20-14+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077190
![PNG](/data/jpeg/tenK5007/BindingDB_50077190.png) (2N-[3-amino(imino)methylphenyl]-2N,4-dimethyl-6-[3...)Show SMILES CN(c1cccc(c1)C(N)=N)c1nc(Oc2cccc(c2)C(N)=N)c(F)c(C)c1F Show InChI InChI=1S/C21H20F2N6O/c1-11-16(22)20(29(2)14-7-3-5-12(9-14)18(24)25)28-21(17(11)23)30-15-8-4-6-13(10-15)19(26)27/h3-10H,1-2H3,(H3,24,25)(H3,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM17278
![PNG](/data/jpeg/tenK1/BindingDB_17278.png) (3-{[6-(3-carbamimidoylphenoxy)-3,5-difluoro-4-meth...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C20H17F2N5O2/c1-10-15(21)19(28-13-6-2-4-11(8-13)17(23)24)27-20(16(10)22)29-14-7-3-5-12(9-14)18(25)26/h2-9H,1H3,(H3,23,24)(H3,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM17283
![PNG](/data/jpeg/tenK1/BindingDB_17283.png) ((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)Show SMILES CC(=N)N1CC[C@@H](C1)Oc1ccc(cc1)[C@H](Cc1ccc2ccc(cc2c1)C(N)=N)C(O)=O |r| Show InChI InChI=1S/C26H28N4O3/c1-16(27)30-11-10-23(15-30)33-22-8-6-19(7-9-22)24(26(31)32)13-17-2-3-18-4-5-20(25(28)29)14-21(18)12-17/h2-9,12,14,23-24,27H,10-11,13,15H2,1H3,(H3,28,29)(H,31,32)/t23-,24-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against factor Xa (FXa) |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077181
![PNG](/data/jpeg/tenK5007/BindingDB_50077181.png) (3-{6-[3-amino(imino)methylphenoxy]-3,5-difluoro-4-...)Show SMILES COc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C20H17F2N5O3/c1-28-16-14(21)19(29-12-6-2-4-10(8-12)17(23)24)27-20(15(16)22)30-13-7-3-5-11(9-13)18(25)26/h2-9H,1H3,(H3,23,24)(H3,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066640
![PNG](/data/jpeg/tenK5006/BindingDB_50066640.png) (3-{6-[3-amino(imino)methylphenoxy]-3,5-difluoro-2-...)Show SMILES NC(=N)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)cc2F)c1 Show InChI InChI=1S/C19H15F2N5O2/c20-14-9-15(21)19(28-13-6-2-4-11(8-13)17(24)25)26-18(14)27-12-5-1-3-10(7-12)16(22)23/h1-9H,(H3,22,23)(H3,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077169
![PNG](/data/jpeg/tenK5007/BindingDB_50077169.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-N,N-dimethyl-nic...)Show SMILES CN(C)C(=O)c1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C22H22N6O3/c1-28(2)22(29)17-9-10-18(30-15-7-3-5-13(11-15)19(23)24)27-21(17)31-16-8-4-6-14(12-16)20(25)26/h3-12H,1-2H3,(H3,23,24)(H3,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50066614
![PNG](/data/jpeg/tenK5006/BindingDB_50066614.png) ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...)Show SMILES NC(=N)c1ccc(\C=C2/CCCC\C(=C/c3ccc(cc3)C(N)=N)C2=O)cc1 Show InChI InChI=1S/C23H24N4O/c24-22(25)17-9-5-15(6-10-17)13-19-3-1-2-4-20(21(19)28)14-16-7-11-18(12-8-16)23(26)27/h5-14H,1-4H2,(H3,24,25)(H3,26,27)/b19-13+,20-14+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077184
![PNG](/data/jpeg/tenK5007/BindingDB_50077184.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-isonicotinic aci...)Show SMILES CCOC(=O)c1cc(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=N)c1 Show InChI InChI=1S/C22H21N5O4/c1-2-29-22(28)15-11-18(30-16-7-3-5-13(9-16)20(23)24)27-19(12-15)31-17-8-4-6-14(10-17)21(25)26/h3-12H,2H2,1H3,(H3,23,24)(H3,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077168
![PNG](/data/jpeg/tenK5007/BindingDB_50077168.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-isonicotinamide ...)Show SMILES NC(=N)c1cccc(Oc2cc(cc(Oc3cccc(c3)C(N)=N)n2)C(N)=O)c1 Show InChI InChI=1S/C20H18N6O3/c21-18(22)11-3-1-5-14(7-11)28-16-9-13(20(25)27)10-17(26-16)29-15-6-2-4-12(8-15)19(23)24/h1-10H,(H3,21,22)(H3,23,24)(H2,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077185
![PNG](/data/jpeg/tenK5007/BindingDB_50077185.png) (6-[6-(3-Carbamimidoyl-phenoxy)-pyrazin-2-yloxy]-py...)Show SMILES NC(=N)c1cccc(Oc2cncc(Oc3cccc(n3)C(N)=N)n2)c1 Show InChI InChI=1S/C17H15N7O2/c18-16(19)10-3-1-4-11(7-10)25-14-8-22-9-15(24-14)26-13-6-2-5-12(23-13)17(20)21/h1-9H,(H3,18,19)(H3,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077172
![PNG](/data/jpeg/tenK5007/BindingDB_50077172.png) (CHEMBL49295 | N-[2,6-Bis-(3-carbamimidoyl-phenoxy)...)Show SMILES CC(=O)Nc1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C21H20N6O3/c1-12(28)26-17-8-9-18(29-15-6-2-4-13(10-15)19(22)23)27-21(17)30-16-7-3-5-14(11-16)20(24)25/h2-11H,1H3,(H3,22,23)(H3,24,25)(H,26,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066626
![PNG](/data/jpeg/tenK5006/BindingDB_50066626.png) (3-{6-[3-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)Show SMILES NC(=N)c1cccc(Oc2cccc(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C19H17N5O2/c20-18(21)12-4-1-6-14(10-12)25-16-8-3-9-17(24-16)26-15-7-2-5-13(11-15)19(22)23/h1-11H,(H3,20,21)(H3,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077186
![PNG](/data/jpeg/tenK5007/BindingDB_50077186.png) (2,6-di[3-amino(imino)methylphenoxy]-3-pyridinamine...)Show SMILES NC(=N)c1cccc(Oc2ccc(N)c(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C19H18N6O2/c20-15-7-8-16(26-13-5-1-3-11(9-13)17(21)22)25-19(15)27-14-6-2-4-12(10-14)18(23)24/h1-10H,20H2,(H3,21,22)(H3,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077171
![PNG](/data/jpeg/tenK5007/BindingDB_50077171.png) (2,6-di[3-amino-N-methyl carboxamide-(imino)methylp...)Show SMILES CNC(=O)Nc1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C21H21N7O3/c1-26-21(29)27-16-8-9-17(30-14-6-2-4-12(10-14)18(22)23)28-20(16)31-15-7-3-5-13(11-15)19(24)25/h2-11H,1H3,(H3,22,23)(H3,24,25)(H2,26,27,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066620
![PNG](/data/jpeg/tenK5006/BindingDB_50066620.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-isonicotinic aci...)Show SMILES NC(=N)c1cccc(Oc2cc(cc(Oc3cccc(c3)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C20H17N5O4/c21-18(22)11-3-1-5-14(7-11)28-16-9-13(20(26)27)10-17(25-16)29-15-6-2-4-12(8-15)19(23)24/h1-10H,(H3,21,22)(H3,23,24)(H,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077180
![PNG](/data/jpeg/tenK5007/BindingDB_50077180.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-N-methyl-isonico...)Show SMILES CNC(=O)c1cc(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=N)c1 Show InChI InChI=1S/C21H20N6O3/c1-26-21(28)14-10-17(29-15-6-2-4-12(8-15)19(22)23)27-18(11-14)30-16-7-3-5-13(9-16)20(24)25/h2-11H,1H3,(H3,22,23)(H3,24,25)(H,26,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077170
![PNG](/data/jpeg/tenK5007/BindingDB_50077170.png) (2,6-di[3-amino-phenyl carboxamide-(imino)methylphe...)Show SMILES NC(=N)c1cccc(Oc2ccc(NC(=O)Nc3ccccc3)c(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C26H23N7O3/c27-23(28)16-6-4-10-19(14-16)35-22-13-12-21(32-26(34)31-18-8-2-1-3-9-18)25(33-22)36-20-11-5-7-17(15-20)24(29)30/h1-15H,(H3,27,28)(H3,29,30)(H2,31,32,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077178
![PNG](/data/jpeg/tenK5007/BindingDB_50077178.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-nicotinic acid |...)Show SMILES NC(=N)c1cccc(Oc2ccc(C(O)=O)c(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C20H17N5O4/c21-17(22)11-3-1-5-13(9-11)28-16-8-7-15(20(26)27)19(25-16)29-14-6-2-4-12(10-14)18(23)24/h1-10H,(H3,21,22)(H3,23,24)(H,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077183
![PNG](/data/jpeg/tenK5007/BindingDB_50077183.png) (2N,6N-di[3-amino(imino)methylphenyl]-2N,4,6N-trime...)Show SMILES CN(c1cccc(c1)C(N)=N)c1nc(N(C)c2cccc(c2)C(N)=N)c(F)c(C)c1F Show InChI InChI=1S/C22H23F2N7/c1-12-17(23)21(30(2)15-8-4-6-13(10-15)19(25)26)29-22(18(12)24)31(3)16-9-5-7-14(11-16)20(27)28/h4-11H,1-3H3,(H3,25,26)(H3,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077170
![PNG](/data/jpeg/tenK5007/BindingDB_50077170.png) (2,6-di[3-amino-phenyl carboxamide-(imino)methylphe...)Show SMILES NC(=N)c1cccc(Oc2ccc(NC(=O)Nc3ccccc3)c(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C26H23N7O3/c27-23(28)16-6-4-10-19(14-16)35-22-13-12-21(32-26(34)31-18-8-2-1-3-9-18)25(33-22)36-20-11-5-7-17(15-20)24(29)30/h1-15H,(H3,27,28)(H3,29,30)(H2,31,32,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077194
![PNG](/data/jpeg/tenK5007/BindingDB_50077194.png) (3-{6-[3-amino(imino)methylphenoxy]-3-trifluorometh...)Show SMILES NC(=N)c1cccc(Oc2ccc(c(Oc3cccc(c3)C(N)=N)n2)C(F)(F)F)c1 Show InChI InChI=1S/C20H16F3N5O2/c21-20(22,23)15-7-8-16(29-13-5-1-3-11(9-13)17(24)25)28-19(15)30-14-6-2-4-12(10-14)18(26)27/h1-10H,(H3,24,25)(H3,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077167
![PNG](/data/jpeg/tenK5007/BindingDB_50077167.png) (2-{3-[2,6-Bis-(3-carbamimidoyl-phenoxy)-pyridin-3-...)Show SMILES NC(=O)CNC(=O)Nc1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C22H22N8O4/c23-17(31)11-28-22(32)29-16-7-8-18(33-14-5-1-3-12(9-14)19(24)25)30-21(16)34-15-6-2-4-13(10-15)20(26)27/h1-10H,11H2,(H2,23,31)(H3,24,25)(H3,26,27)(H2,28,29,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077191
![PNG](/data/jpeg/tenK5007/BindingDB_50077191.png) (6-[2-(3-Carbamimidoyl-phenoxy)-pyrimidin-4-yloxy]-...)Show SMILES NC(=N)c1cccc(Oc2nccc(Oc3cccc(n3)C(N)=N)n2)c1 Show InChI InChI=1S/C17H15N7O2/c18-15(19)10-3-1-4-11(9-10)25-17-22-8-7-14(24-17)26-13-6-2-5-12(23-13)16(20)21/h1-9H,(H3,18,19)(H3,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077189
![PNG](/data/jpeg/tenK5007/BindingDB_50077189.png) (CHEMBL295263 | N-[2,6-Bis-(3-carbamimidoyl-phenoxy...)Show SMILES NC(=N)c1cccc(Oc2ccc(NC(=O)c3ccccc3)c(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C26H22N6O3/c27-23(28)17-8-4-10-19(14-17)34-22-13-12-21(31-25(33)16-6-2-1-3-7-16)26(32-22)35-20-11-5-9-18(15-20)24(29)30/h1-15H,(H3,27,28)(H3,29,30)(H,31,33) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077165
![PNG](/data/jpeg/tenK5007/BindingDB_50077165.png) (2-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)Show InChI InChI=1S/C19H17N5O2/c20-18(21)12-8-10-13(11-9-12)25-16-6-3-7-17(24-16)26-15-5-2-1-4-14(15)19(22)23/h1-11H,(H3,20,21)(H3,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066629
![PNG](/data/jpeg/tenK5006/BindingDB_50066629.png) (3-{6-[3-amino(imino)methylphenoxy]-3,5-dichloro-2-...)Show SMILES NC(=N)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(Cl)cc2Cl)c1 Show InChI InChI=1S/C19H15Cl2N5O2/c20-14-9-15(21)19(28-13-6-2-4-11(8-13)17(24)25)26-18(14)27-12-5-1-3-10(7-12)16(22)23/h1-9H,(H3,22,23)(H3,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077173
![PNG](/data/jpeg/tenK5007/BindingDB_50077173.png) (CHEMBL48595 | N-{2,6-di[3-amino(imino)methylphenox...)Show SMILES CS(=O)(=O)Nc1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C20H20N6O4S/c1-31(27,28)26-16-8-9-17(29-14-6-2-4-12(10-14)18(21)22)25-20(16)30-15-7-3-5-13(11-15)19(23)24/h2-11,26H,1H3,(H3,21,22)(H3,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077192
![PNG](/data/jpeg/tenK5007/BindingDB_50077192.png) (6-[6-(3-Carbamimidoyl-phenoxy)-4-oxy-pyrazin-2-ylo...)Show SMILES NC(=N)c1cccc(Oc2c[n+]([O-])cc(Oc3cccc(n3)C(N)=N)n2)c1 Show InChI InChI=1S/C17H15N7O3/c18-16(19)10-3-1-4-11(7-10)26-14-8-24(25)9-15(23-14)27-13-6-2-5-12(22-13)17(20)21/h1-9H,(H3,18,19)(H3,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077179
![PNG](/data/jpeg/tenK5007/BindingDB_50077179.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-nicotinic acid e...)Show SMILES CCOC(=O)c1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C22H21N5O4/c1-2-29-22(28)17-9-10-18(30-15-7-3-5-13(11-15)19(23)24)27-21(17)31-16-8-4-6-14(12-16)20(25)26/h3-12H,2H2,1H3,(H3,23,24)(H3,25,26) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM17283
![PNG](/data/jpeg/tenK1/BindingDB_17283.png) ((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)Show SMILES CC(=N)N1CC[C@@H](C1)Oc1ccc(cc1)[C@H](Cc1ccc2ccc(cc2c1)C(N)=N)C(O)=O |r| Show InChI InChI=1S/C26H28N4O3/c1-16(27)30-11-10-23(15-30)33-22-8-6-19(7-9-22)24(26(31)32)13-17-2-3-18-4-5-20(25(28)29)14-21(18)12-17/h2-9,12,14,23-24,27H,10-11,13,15H2,1H3,(H3,28,29)(H,31,32)/t23-,24-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077174
![PNG](/data/jpeg/tenK5007/BindingDB_50077174.png) (6-[6-(3-Carbamimidoyl-phenoxy)-5-oxo-1,2,5,6-tetra...)Show SMILES NC(=N)c1cccc(OC2N=C(CNC2=O)Oc2cccc(n2)C(N)=N)c1 |c:10| Show InChI InChI=1S/C17H17N7O3/c18-14(19)9-3-1-4-10(7-9)26-17-16(25)22-8-13(24-17)27-12-6-2-5-11(23-12)15(20)21/h1-7,17H,8H2,(H3,18,19)(H3,20,21)(H,22,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077188
![PNG](/data/jpeg/tenK5007/BindingDB_50077188.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-N-methyl-nicotin...)Show SMILES CNC(=O)c1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C21H20N6O3/c1-26-20(28)16-8-9-17(29-14-6-2-4-12(10-14)18(22)23)27-21(16)30-15-7-3-5-13(11-15)19(24)25/h2-11H,1H3,(H3,22,23)(H3,24,25)(H,26,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077189
![PNG](/data/jpeg/tenK5007/BindingDB_50077189.png) (CHEMBL295263 | N-[2,6-Bis-(3-carbamimidoyl-phenoxy...)Show SMILES NC(=N)c1cccc(Oc2ccc(NC(=O)c3ccccc3)c(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C26H22N6O3/c27-23(28)17-8-4-10-19(14-17)34-22-13-12-21(31-25(33)16-6-2-1-3-7-16)26(32-22)35-20-11-5-9-18(15-20)24(29)30/h1-15H,(H3,27,28)(H3,29,30)(H,31,33) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077167
![PNG](/data/jpeg/tenK5007/BindingDB_50077167.png) (2-{3-[2,6-Bis-(3-carbamimidoyl-phenoxy)-pyridin-3-...)Show SMILES NC(=O)CNC(=O)Nc1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C22H22N8O4/c23-17(31)11-28-22(32)29-16-7-8-18(33-14-5-1-3-12(9-14)19(24)25)30-21(16)34-15-6-2-4-13(10-15)20(26)27/h1-10H,11H2,(H2,23,31)(H3,24,25)(H3,26,27)(H2,28,29,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077182
![PNG](/data/jpeg/tenK5007/BindingDB_50077182.png) (2-{3-[3-amino(imino)methylphenoxy]-4-nitrophenoxy}...)Show SMILES NC(=N)c1cccc(Oc2cc(Oc3ccccc3C(N)=N)ccc2[N+]([O-])=O)c1 Show InChI InChI=1S/C20H17N5O4/c21-19(22)12-4-3-5-13(10-12)29-18-11-14(8-9-16(18)25(26)27)28-17-7-2-1-6-15(17)20(23)24/h1-11H,(H3,21,22)(H3,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50077183
![PNG](/data/jpeg/tenK5007/BindingDB_50077183.png) (2N,6N-di[3-amino(imino)methylphenyl]-2N,4,6N-trime...)Show SMILES CN(c1cccc(c1)C(N)=N)c1nc(N(C)c2cccc(c2)C(N)=N)c(F)c(C)c1F Show InChI InChI=1S/C22H23F2N7/c1-12-17(23)21(30(2)15-8-4-6-13(10-15)19(25)26)29-22(18(12)24)31(3)16-9-5-7-14(11-16)20(27)28/h4-11H,1-3H3,(H3,25,26)(H3,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against human thrombin (FIIa) |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077183
![PNG](/data/jpeg/tenK5007/BindingDB_50077183.png) (2N,6N-di[3-amino(imino)methylphenyl]-2N,4,6N-trime...)Show SMILES CN(c1cccc(c1)C(N)=N)c1nc(N(C)c2cccc(c2)C(N)=N)c(F)c(C)c1F Show InChI InChI=1S/C22H23F2N7/c1-12-17(23)21(30(2)15-8-4-6-13(10-15)19(25)26)29-22(18(12)24)31(3)16-9-5-7-14(11-16)20(27)28/h4-11H,1-3H3,(H3,25,26)(H3,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066618
![PNG](/data/jpeg/tenK5006/BindingDB_50066618.png) (4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)Show SMILES NC(=N)c1ccc(Oc2cccc(Oc3ccc(cc3)C(N)=N)n2)cc1 Show InChI InChI=1S/C19H17N5O2/c20-18(21)12-4-8-14(9-5-12)25-16-2-1-3-17(24-16)26-15-10-6-13(7-11-15)19(22)23/h1-11H,(H3,20,21)(H3,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50066614
![PNG](/data/jpeg/tenK5006/BindingDB_50066614.png) ((E,E)-2,7-Bis(4-amidinobenzylidine)cycloheptan-1-o...)Show SMILES NC(=N)c1ccc(\C=C2/CCCC\C(=C/c3ccc(cc3)C(N)=N)C2=O)cc1 Show InChI InChI=1S/C23H24N4O/c24-22(25)17-9-5-15(6-10-17)13-19-3-1-2-4-20(21(19)28)14-16-7-11-18(12-8-16)23(26)27/h5-14H,1-4H2,(H3,24,25)(H3,26,27)/b19-13+,20-14+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against human thrombin (FIIa) |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50066618
![PNG](/data/jpeg/tenK5006/BindingDB_50066618.png) (4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)Show SMILES NC(=N)c1ccc(Oc2cccc(Oc3ccc(cc3)C(N)=N)n2)cc1 Show InChI InChI=1S/C19H17N5O2/c20-18(21)12-4-8-14(9-5-12)25-16-2-1-3-17(24-16)26-15-10-6-13(7-11-15)19(22)23/h1-11H,(H3,20,21)(H3,22,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against human thrombin (FIIa) |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50066620
![PNG](/data/jpeg/tenK5006/BindingDB_50066620.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-isonicotinic aci...)Show SMILES NC(=N)c1cccc(Oc2cc(cc(Oc3cccc(c3)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C20H17N5O4/c21-18(22)11-3-1-5-14(7-11)28-16-9-13(20(26)27)10-17(25-16)29-15-6-2-4-12(8-15)19(23)24/h1-10H,(H3,21,22)(H3,23,24)(H,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077176
![PNG](/data/jpeg/tenK5007/BindingDB_50077176.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-nicotinamide | C...)Show SMILES NC(=N)c1cccc(Oc2ccc(C(N)=O)c(Oc3cccc(c3)C(N)=N)n2)c1 Show InChI InChI=1S/C20H18N6O3/c21-17(22)11-3-1-5-13(9-11)28-16-8-7-15(19(25)27)20(26-16)29-14-6-2-4-12(10-14)18(23)24/h1-10H,(H3,21,22)(H3,23,24)(H2,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066631
![PNG](/data/jpeg/tenK5006/BindingDB_50066631.png) (4-[3,5-Dichloro-6-(4-diaminomethyl-phenoxy)-pyridi...)Show SMILES NC(=N)c1ccc(Oc2nc(Oc3ccc(cc3)C(N)=N)c(Cl)cc2Cl)cc1 Show InChI InChI=1S/C19H15Cl2N5O2/c20-14-9-15(21)19(28-13-7-3-11(4-8-13)17(24)25)26-18(14)27-12-5-1-10(2-6-12)16(22)23/h1-9H,(H3,22,23)(H3,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077166
![PNG](/data/jpeg/tenK5007/BindingDB_50077166.png) (2N-[3-amino(imino)methylphenyl]-6-[3-amino(imino)m...)Show SMILES Cc1c(F)c(Nc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C20H18F2N6O/c1-10-15(21)19(27-13-6-2-4-11(8-13)17(23)24)28-20(16(10)22)29-14-7-3-5-12(9-14)18(25)26/h2-9H,1H3,(H3,23,24)(H3,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077190
![PNG](/data/jpeg/tenK5007/BindingDB_50077190.png) (2N-[3-amino(imino)methylphenyl]-2N,4-dimethyl-6-[3...)Show SMILES CN(c1cccc(c1)C(N)=N)c1nc(Oc2cccc(c2)C(N)=N)c(F)c(C)c1F Show InChI InChI=1S/C21H20F2N6O/c1-11-16(22)20(29(2)14-7-3-5-12(9-14)18(24)25)28-21(17(11)23)30-15-8-4-6-13(10-15)19(26)27/h3-10H,1-2H3,(H3,24,25)(H3,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50077193
![PNG](/data/jpeg/tenK5007/BindingDB_50077193.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-N-carbamoylmethy...)Show SMILES NC(=O)CNC(=O)c1ccc(Oc2cccc(c2)C(N)=N)nc1Oc1cccc(c1)C(N)=N Show InChI InChI=1S/C22H21N7O4/c23-17(30)11-28-21(31)16-7-8-18(32-14-5-1-3-12(9-14)19(24)25)29-22(16)33-15-6-2-4-13(10-15)20(26)27/h1-10H,11H2,(H2,23,30)(H3,24,25)(H3,26,27)(H,28,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against Coagulation factor X |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077180
![PNG](/data/jpeg/tenK5007/BindingDB_50077180.png) (2,6-Bis-(3-carbamimidoyl-phenoxy)-N-methyl-isonico...)Show SMILES CNC(=O)c1cc(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=N)c1 Show InChI InChI=1S/C21H20N6O3/c1-26-21(28)14-10-17(29-15-6-2-4-12(8-15)19(22)23)27-18(11-14)30-16-7-3-5-13(9-16)20(24)25/h2-11H,1H3,(H3,22,23)(H3,24,25)(H,26,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077191
![PNG](/data/jpeg/tenK5007/BindingDB_50077191.png) (6-[2-(3-Carbamimidoyl-phenoxy)-pyrimidin-4-yloxy]-...)Show SMILES NC(=N)c1cccc(Oc2nccc(Oc3cccc(n3)C(N)=N)n2)c1 Show InChI InChI=1S/C17H15N7O2/c18-15(19)10-3-1-4-11(9-10)25-17-22-8-7-14(24-17)26-13-6-2-5-12(23-13)16(20)21/h1-9H,(H3,18,19)(H3,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50077174
![PNG](/data/jpeg/tenK5007/BindingDB_50077174.png) (6-[6-(3-Carbamimidoyl-phenoxy)-5-oxo-1,2,5,6-tetra...)Show SMILES NC(=N)c1cccc(OC2N=C(CNC2=O)Oc2cccc(n2)C(N)=N)c1 |c:10| Show InChI InChI=1S/C17H17N7O3/c18-14(19)9-3-1-4-10(7-9)26-17-16(25)22-8-13(24-17)27-12-6-2-5-11(23-12)15(20)21/h1-7,17H,8H2,(H3,18,19)(H3,20,21)(H,22,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description Compound was tested for inhibition activity against bovine trypsin. |
J Med Chem 42: 1749-56 (1999)
Article DOI: 10.1021/jm980667k BindingDB Entry DOI: 10.7270/Q2FX78NF |
More data for this Ligand-Target Pair | |