Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091878 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091882 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-1-oxo-pe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091888 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-4-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091883 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-4-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091889 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-hexanoyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50048319 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50403795 (CHEMBL2115491) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091887 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091885 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091877 ((S)-3-Biphenyl-4-yl-2-{[1-((R)-2-mercapto-hexanoyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091879 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-3-hydroxy-2-mercapt...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091880 ((S)-3-Biphenyl-4-yl-2-{[1-((R)-2-mercapto-4-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091890 ((S)-3-Biphenyl-4-yl-2-{[1-((R)-2-mercapto-pentanoy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091884 ((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-phenyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50403794 (CHEMBL2114468) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50091886 ((S)-3-Biphenyl-4-yl-2-{[1-(2-mercapto-2-methyl-pro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of human Endothelin converting Enzyme-1 activity | Bioorg Med Chem Lett 10: 2037-9 (2001) BindingDB Entry DOI: 10.7270/Q2K35SW0 | |||||||||||
More data for this Ligand-Target Pair |