Found 28 hits Enz. Inhib. hit(s) with all data for entry = 50026010 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266158
(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C21H20N2O2/c1-23(2)13-14-24-17-10-7-16(8-11-17)21-22-20-18-6-4-3-5-15(18)9-12-19(20)25-21/h3-12H,13-14H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266161
(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H24N2O2/c1-4-14-26(15-5-1)16-17-27-20-11-8-19(9-12-20)24-25-23-21-7-3-2-6-18(21)10-13-22(23)28-24/h2-3,6-13H,1,4-5,14-17H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266161
(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H24N2O2/c1-4-14-26(15-5-1)16-17-27-20-11-8-19(9-12-20)24-25-23-21-7-3-2-6-18(21)10-13-22(23)28-24/h2-3,6-13H,1,4-5,14-17H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266158
(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C21H20N2O2/c1-23(2)13-14-24-17-10-7-16(8-11-17)21-22-20-18-6-4-3-5-15(18)9-12-19(20)25-21/h3-12H,13-14H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266231
(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C22H22N2O2/c1-24(2)14-5-15-25-18-11-8-17(9-12-18)22-23-21-19-7-4-3-6-16(19)10-13-20(21)26-22/h3-4,6-13H,5,14-15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266160
(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C23H22N2O2/c1-2-6-20-17(5-1)9-12-21-22(20)24-23(27-21)18-7-10-19(11-8-18)26-16-15-25-13-3-4-14-25/h1-2,5-12H,3-4,13-16H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266159
(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)Show InChI InChI=1S/C23H24N2O2/c1-3-25(4-2)15-16-26-19-12-9-18(10-13-19)23-24-22-20-8-6-5-7-17(20)11-14-21(22)27-23/h5-14H,3-4,15-16H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266231
(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C22H22N2O2/c1-24(2)14-5-15-25-18-11-8-17(9-12-18)22-23-21-19-7-4-3-6-16(19)10-13-20(21)26-22/h3-4,6-13H,5,14-15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266160
(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C23H22N2O2/c1-2-6-20-17(5-1)9-12-21-22(20)24-23(27-21)18-7-10-19(11-8-18)26-16-15-25-13-3-4-14-25/h1-2,5-12H,3-4,13-16H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266232
(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-26(4-2)16-7-17-27-20-13-10-19(11-14-20)24-25-23-21-9-6-5-8-18(21)12-15-22(23)28-24/h5-6,8-15H,3-4,7,16-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266232
(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-26(4-2)16-7-17-27-20-13-10-19(11-14-20)24-25-23-21-9-6-5-8-18(21)12-15-22(23)28-24/h5-6,8-15H,3-4,7,16-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266162
(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)Show SMILES CCCCN(C)CCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-4-15-26(2)16-17-27-20-12-9-19(10-13-20)24-25-23-21-8-6-5-7-18(21)11-14-22(23)28-24/h5-14H,3-4,15-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266162
(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)Show SMILES CCCCN(C)CCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-4-15-26(2)16-17-27-20-12-9-19(10-13-20)24-25-23-21-8-6-5-7-18(21)11-14-22(23)28-24/h5-14H,3-4,15-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266159
(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)Show InChI InChI=1S/C23H24N2O2/c1-3-25(4-2)15-16-26-19-12-9-18(10-13-19)23-24-22-20-8-6-5-7-17(20)11-14-21(22)27-23/h5-14H,3-4,15-16H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266161
(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H24N2O2/c1-4-14-26(15-5-1)16-17-27-20-11-8-19(9-12-20)24-25-23-21-7-3-2-6-18(21)10-13-22(23)28-24/h2-3,6-13H,1,4-5,14-17H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266161
(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H24N2O2/c1-4-14-26(15-5-1)16-17-27-20-11-8-19(9-12-20)24-25-23-21-7-3-2-6-18(21)10-13-22(23)28-24/h2-3,6-13H,1,4-5,14-17H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266162
(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)Show SMILES CCCCN(C)CCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-4-15-26(2)16-17-27-20-12-9-19(10-13-20)24-25-23-21-8-6-5-7-18(21)11-14-22(23)28-24/h5-14H,3-4,15-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266162
(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)Show SMILES CCCCN(C)CCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-4-15-26(2)16-17-27-20-12-9-19(10-13-20)24-25-23-21-8-6-5-7-18(21)11-14-22(23)28-24/h5-14H,3-4,15-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266232
(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-26(4-2)16-7-17-27-20-13-10-19(11-14-20)24-25-23-21-9-6-5-8-18(21)12-15-22(23)28-24/h5-6,8-15H,3-4,7,16-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266232
(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C24H26N2O2/c1-3-26(4-2)16-7-17-27-20-13-10-19(11-14-20)24-25-23-21-9-6-5-8-18(21)12-15-22(23)28-24/h5-6,8-15H,3-4,7,16-17H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266231
(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C22H22N2O2/c1-24(2)14-5-15-25-18-11-8-17(9-12-18)22-23-21-19-7-4-3-6-16(19)10-13-20(21)26-22/h3-4,6-13H,5,14-15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266158
(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C21H20N2O2/c1-23(2)13-14-24-17-10-7-16(8-11-17)21-22-20-18-6-4-3-5-15(18)9-12-19(20)25-21/h3-12H,13-14H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266231
(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C22H22N2O2/c1-24(2)14-5-15-25-18-11-8-17(9-12-18)22-23-21-19-7-4-3-6-16(19)10-13-20(21)26-22/h3-4,6-13H,5,14-15H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266158
(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)Show InChI InChI=1S/C21H20N2O2/c1-23(2)13-14-24-17-10-7-16(8-11-17)21-22-20-18-6-4-3-5-15(18)9-12-19(20)25-21/h3-12H,13-14H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266159
(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)Show InChI InChI=1S/C23H24N2O2/c1-3-25(4-2)15-16-26-19-12-9-18(10-13-19)23-24-22-20-8-6-5-7-17(20)11-14-21(22)27-23/h5-14H,3-4,15-16H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266159
(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)Show InChI InChI=1S/C23H24N2O2/c1-3-25(4-2)15-16-26-19-12-9-18(10-13-19)23-24-22-20-8-6-5-7-17(20)11-14-21(22)27-23/h5-14H,3-4,15-16H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266160
(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C23H22N2O2/c1-2-6-20-17(5-1)9-12-21-22(20)24-23(27-21)18-7-10-19(11-8-18)26-16-15-25-13-3-4-14-25/h1-2,5-12H,3-4,13-16H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100 |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50266160
(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)Show SMILES C(CN1CCCC1)Oc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1 Show InChI InChI=1S/C23H22N2O2/c1-2-6-20-17(5-1)9-12-21-22(20)24-23(27-21)18-7-10-19(11-8-18)26-16-15-25-13-3-4-14-25/h1-2,5-12H,3-4,13-16H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute
Curated by ChEMBL
| Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity |
Eur J Med Chem 44: 109-16 (2008)
Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602 |
More data for this Ligand-Target Pair | |