Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297767 ((R)-1-(2-(5-(4-(ethylsulfonyl)phenoxy)-2-(pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297790 ((2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H-benzo[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297768 (1-(2-(5-(3-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 930 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297769 (1-(2-(5-phenoxy-2-(pyridin-2-yl)-1H-benzo[d]imidaz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297770 (1-(2-(5-(4-(methylsulfonyl)phenoxy)-2-(pyridin-2-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297771 (1-(2-(5-(biphenyl-4-yloxy)-2-(pyridin-2-yl)-1H-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297772 (1-(2-(5-(4-(isopropylsulfonyl)phenoxy)-2-(pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297773 (4-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297774 (1-(2-(5-(4-methoxyphenoxy)-2-(pyridin-2-yl)-1H-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297775 (3-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297776 (4-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297777 (1-(2-(5-(4-nitrophenoxy)-2-(pyridin-2-yl)-1H-benzo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297779 (1-(2-(5-(3-methoxyphenoxy)-2-(pyridin-2-yl)-1H-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297780 (CHEMBL556309 | ethyl 4-(6-(1-acetylpyrrolidin-2-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297781 (1-(2-(5-(2-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297782 (1-(2-(5-(biphenyl-3-yloxy)-2-(pyridin-2-yl)-1H-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297783 (1-(2-(5-(2-methoxyphenoxy)-2-(pyridin-2-yl)-1H-ben...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297784 (2-(6-(1-acetylpyrrolidin-2-yl)-2-(pyridin-2-yl)-1H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297785 (1-(2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297786 (CHEMBL550474 | ethyl 2-(5-(4-fluorophenoxy)-2-(pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.47E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297787 (1-(2-(5-(4-fluorophenoxy)-2-(pyridin-2-yl)-1H-benz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297788 (5-(4-fluorophenoxy)-6-(1-(methylsulfonyl)pyrrolidi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297789 (CHEMBL560204 | N-ethyl-2-(5-(4-fluorophenoxy)-2-(p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hexokinase-4 (Homo sapiens (Human)) | BDBM50297767 ((R)-1-(2-(5-(4-(ethylsulfonyl)phenoxy)-2-(pyridin-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 630 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Activation of flag-tagged recombinant human liver glucokinase expressed in Escherichia coli assessed as glucose-6-phosphate dehydrogenase by spectrop... | Bioorg Med Chem Lett 19: 4450-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.038 BindingDB Entry DOI: 10.7270/Q27H1JNG | |||||||||||
More data for this Ligand-Target Pair |