Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HTH-type transcriptional regulator EthR (Mycobacterium smegmatis (strain ATCC 700084 / mc(2...) | BDBM50395186![]() (CHEMBL1612418) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France Curated by ChEMBL | Assay Description Inhibition at EthR in Mycobacterium smegmatis mc2 155 assessed as reactivation of beta-glucuronidase activity measured over 48 hrs by Spectrophotomet... | J Med Chem 55: 6391-402 (2012) Article DOI: 10.1021/jm300377g BindingDB Entry DOI: 10.7270/Q2S183MF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis) | BDBM50395182![]() (CHEMBL2163975) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethio... | J Med Chem 55: 6391-402 (2012) Article DOI: 10.1021/jm300377g BindingDB Entry DOI: 10.7270/Q2S183MF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis) | BDBM50395183![]() (CHEMBL2163969) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethio... | J Med Chem 55: 6391-402 (2012) Article DOI: 10.1021/jm300377g BindingDB Entry DOI: 10.7270/Q2S183MF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis) | BDBM50395185![]() (CHEMBL2164318) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethio... | J Med Chem 55: 6391-402 (2012) Article DOI: 10.1021/jm300377g BindingDB Entry DOI: 10.7270/Q2S183MF | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis) | BDBM50395186![]() (CHEMBL1612418) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethio... | J Med Chem 55: 6391-402 (2012) Article DOI: 10.1021/jm300377g BindingDB Entry DOI: 10.7270/Q2S183MF | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis) | BDBM50395181![]() (CHEMBL2164306) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethio... | J Med Chem 55: 6391-402 (2012) Article DOI: 10.1021/jm300377g BindingDB Entry DOI: 10.7270/Q2S183MF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTH-type transcriptional regulator EthR (Mycobacterium tuberculosis) | BDBM50395184![]() (CHEMBL2164319) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a |
Universit£ Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethio... | J Med Chem 55: 6391-402 (2012) Article DOI: 10.1021/jm300377g BindingDB Entry DOI: 10.7270/Q2S183MF | |||||||||||
More data for this Ligand-Target Pair |