Compile Data Set for Download or QSAR

Found 25 hits Enz. Inhib. hit(s) with all data for entry = 50045319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50056694 (CHEMBL3326943) Show SMILES CCCCCn1c(N)nc2c(OCc3ccccc3)cccc12 Show InChI InChI=1S/C19H23N3O/c1-2-3-7-13-22-16-11-8-12-17(18(16)21-19(22)20)23-14-15-9-5-4-6-10-15/h4-6,8-12H,2-3,7,13-14H2,1H3,(H2,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50056693 (CHEMBL3326942) Show SMILES CCCCCn1c(N)nc2c(Cc3ccccc3)cccc12 Show InChI InChI=1S/C19H23N3/c1-2-3-7-13-22-17-12-8-11-16(18(17)21-19(22)20)14-15-9-5-4-6-10-15/h4-6,8-12H,2-3,7,13-14H2,1H3,(H2,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50056692 (CHEMBL3326941) Show SMILES CCCCCn1c(N)nc2c(cccc12)-c1ccccc1 Show InChI InChI=1S/C18H21N3/c1-2-3-7-13-21-16-12-8-11-15(17(16)20-18(21)19)14-9-5-4-6-10-14/h4-6,8-12H,2-3,7,13H2,1H3,(H2,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50056691 (CHEMBL3326924) Show SMILES CCCCCn1c(N)nc2ccc3ccccc3c12 Show InChI InChI=1S/C16H19N3/c1-2-3-6-11-19-15-13-8-5-4-7-12(13)9-10-14(15)18-16(19)17/h4-5,7-10H,2-3,6,11H2,1H3,(H2,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50056690 (CHEMBL3326923) Show SMILES CCCCCn1c(N)nc2cc3ccccc3cc12 Show InChI InChI=1S/C16H19N3/c1-2-3-6-9-19-15-11-13-8-5-4-7-12(13)10-14(15)18-16(19)17/h4-5,7-8,10-11H,2-3,6,9H2,1H3,(H2,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM50056689 (CHEMBL3326922) Show SMILES CCCCCn1c(NC(C)=O)nc2ccccc12 Show InChI InChI=1S/C14H19N3O/c1-3-4-7-10-17-13-9-6-5-8-12(13)16-14(17)15-11(2)18/h5-6,8-9H,3-4,7,10H2,1-2H3,(H,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM50056694 (CHEMBL3326943) Show SMILES CCCCCn1c(N)nc2c(OCc3ccccc3)cccc12 Show InChI InChI=1S/C19H23N3O/c1-2-3-7-13-22-16-11-8-12-17(18(16)21-19(22)20)23-14-15-9-5-4-6-10-15/h4-6,8-12H,2-3,7,13-14H2,1H3,(H2,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM50056693 (CHEMBL3326942) Show SMILES CCCCCn1c(N)nc2c(Cc3ccccc3)cccc12 Show InChI InChI=1S/C19H23N3/c1-2-3-7-13-22-17-12-8-11-16(18(17)21-19(22)20)14-15-9-5-4-6-10-15/h4-6,8-12H,2-3,7,13-14H2,1H3,(H2,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM50056692 (CHEMBL3326941) Show SMILES CCCCCn1c(N)nc2c(cccc12)-c1ccccc1 Show InChI InChI=1S/C18H21N3/c1-2-3-7-13-21-16-12-8-11-15(17(16)20-18(21)19)14-9-5-4-6-10-14/h4-6,8-12H,2-3,7,13H2,1H3,(H2,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM50056691 (CHEMBL3326924) Show SMILES CCCCCn1c(N)nc2ccc3ccccc3c12 Show InChI InChI=1S/C16H19N3/c1-2-3-6-11-19-15-13-8-5-4-7-12(13)9-10-14(15)18-16(19)17/h4-5,7-10H,2-3,6,11H2,1H3,(H2,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM50056690 (CHEMBL3326923) Show SMILES CCCCCn1c(N)nc2cc3ccccc3cc12 Show InChI InChI=1S/C16H19N3/c1-2-3-6-9-19-15-11-13-8-5-4-7-12(13)10-14(15)18-16(19)17/h4-5,7-8,10-11H,2-3,6,9H2,1H3,(H2,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50056689 (CHEMBL3326922) Show SMILES CCCCCn1c(NC(C)=O)nc2ccccc12 Show InChI InChI=1S/C14H19N3O/c1-3-4-7-10-17-13-9-6-5-8-12(13)16-14(17)15-11(2)18/h5-6,8-9H,3-4,7,10H2,1-2H3,(H,15,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056705 (CHEMBL3326944) Show SMILES CCCCCn1c(N)nc2c(O)cccc12 Show InChI InChI=1S/C12H17N3O/c1-2-3-4-8-15-9-6-5-7-10(16)11(9)14-12(15)13/h5-7,16H,2-4,8H2,1H3,(H2,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056704 (CHEMBL3326940) Show SMILES CCCCCn1c(N)nc2c(cccc12)N(C)C Show InChI InChI=1S/C14H22N4/c1-4-5-6-10-18-12-9-7-8-11(17(2)3)13(12)16-14(18)15/h7-9H,4-6,10H2,1-3H3,(H2,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.12E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056703 (CHEMBL3326939) Show SMILES CCCCCn1c(N)nc2c(CC)cccc12 Show InChI InChI=1S/C14H21N3/c1-3-5-6-10-17-12-9-7-8-11(4-2)13(12)16-14(17)15/h7-9H,3-6,10H2,1-2H3,(H2,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056702 (CHEMBL3326934) Show SMILES CCCCCn1c(N)nc2c(OC)cccc12 Show InChI InChI=1S/C13H19N3O/c1-3-4-5-9-16-10-7-6-8-11(17-2)12(10)15-13(16)14/h6-8H,3-5,9H2,1-2H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.74E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056701 (CHEMBL3326933) Show SMILES CCCCCn1c(N)nc2cccc(C)c12 Show InChI InChI=1S/C13H19N3/c1-3-4-5-9-16-12-10(2)7-6-8-11(12)15-13(16)14/h6-8H,3-5,9H2,1-2H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.61E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056700 (CHEMBL3326932) Show SMILES CCCCCn1c(N)nc2ccc(C)cc12 Show InChI InChI=1S/C13H19N3/c1-3-4-5-8-16-12-9-10(2)6-7-11(12)15-13(16)14/h6-7,9H,3-5,8H2,1-2H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.21E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056699 (CHEMBL3326931) Show SMILES CCCCCn1c(N)nc2cc(C)ccc12 Show InChI InChI=1S/C13H19N3/c1-3-4-5-8-16-12-7-6-10(2)9-11(12)15-13(16)14/h6-7,9H,3-5,8H2,1-2H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056698 (CHEMBL3326930) Show SMILES CCCCCn1c(N)nc2c(C)cccc12 Show InChI InChI=1S/C13H19N3/c1-3-4-5-9-16-11-8-6-7-10(2)12(11)15-13(16)14/h6-8H,3-5,9H2,1-2H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056697 (CHEMBL3326925) Show SMILES CCCCCn1c(N)nc2c1ccc1ccccc21 Show InChI InChI=1S/C16H19N3/c1-2-3-6-11-19-14-10-9-12-7-4-5-8-13(12)15(14)18-16(19)17/h4-5,7-10H,2-3,6,11H2,1H3,(H2,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056696 (CHEMBL2270741) Show SMILES CCCCCCn1c(N)nc2ccccc12 Show InChI InChI=1S/C13H19N3/c1-2-3-4-7-10-16-12-9-6-5-8-11(12)15-13(16)14/h5-6,8-9H,2-4,7,10H2,1H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056695 (CHEMBL3326918) Show SMILES CCCCCn1c(N)nc2ccccc12 Show InChI InChI=1S/C12H17N3/c1-2-3-6-9-15-11-8-5-4-7-10(11)14-12(15)13/h4-5,7-8H,2-3,6,9H2,1H3,(H2,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.23E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056706 (CHEMBL3326946) Show SMILES CCCCCn1c(N)nc2c(N)cccc12 Show InChI InChI=1S/C12H18N4/c1-2-3-4-8-16-10-7-5-6-9(13)11(10)15-12(16)14/h5-7H,2-4,8,13H2,1H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM62988 ((1-butylbenzimidazol-2-yl)amine;hydrochloride | 1-...) Show SMILES CCCCn1c(N)nc2ccccc12 Show InChI InChI=1S/C11H15N3/c1-2-3-8-14-10-7-5-4-6-9(10)13-11(14)12/h4-7H,2-3,8H2,1H3,(H2,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair