Compile Data Set for Download or QSAR

Found 122 hits Enz. Inhib. hit(s) with all data for entry = 7278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185975 (US9163008, 64 | US9656968, Compound 64) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H17ClFN5O3/c1-10(18(23)28)25-17-9-15(19(24)29)26-20(27-17)11-2-5-13(6-3-11)30-16-7-4-12(21)8-14(16)22/h2-10H,1H3,(H2,23,28)(H2,24,29)(H,25,26,27)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185953 (US9163008, 42 | US9656968, Compound 42) Show SMILES C[C@@H](CO)Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O |r| Show InChI InChI=1S/C20H19FN4O3/c1-12(11-26)23-18-10-17(19(22)27)24-20(25-18)13-2-6-15(7-3-13)28-16-8-4-14(21)5-9-16/h2-10,12,26H,11H2,1H3,(H2,22,27)(H,23,24,25)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185925 (US9163008, 14 | US9656968, Compound 14) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H18F3N5O3/c1-11(18(25)30)27-17-10-16(19(26)31)28-20(29-17)12-2-6-14(7-3-12)32-15-8-4-13(5-9-15)21(22,23)24/h2-11H,1H3,(H2,25,30)(H2,26,31)(H,27,28,29)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185918 (US9163008, 7 | US9656968, Compound 7) Show SMILES NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C21H18FN5O3/c22-13-3-7-15(8-4-13)30-14-5-1-12(2-6-14)20-26-17(19(23)28)11-18(27-20)25-16-9-10-24-21(16)29/h1-8,11,16H,9-10H2,(H2,23,28)(H,24,29)(H,25,26,27)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	53	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185967 (US9163008, 56 | US9656968, Compound 56) Show SMILES C[C@H](Oc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H17FN4O4/c1-11(18(22)26)28-17-10-16(19(23)27)24-20(25-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H2,22,26)(H2,23,27)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	53	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM186009 (US9163008, 98 | US9656968, Compound 98) Show SMILES C[C@H](Oc1cc(nc(n1)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H17F3N4O4/c1-11(18(25)29)31-17-10-16(19(26)30)27-20(28-17)12-2-6-14(7-3-12)32-15-8-4-13(5-9-15)21(22,23)24/h2-11H,1H3,(H2,25,29)(H2,26,30)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	54	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185912 (US9163008, 1 | US9656968, Compound 1) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H18FN5O3/c1-11(18(22)27)24-17-10-16(19(23)28)25-20(26-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H2,22,27)(H2,23,28)(H,24,25,26)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	57	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185949 (US9163008, 38 | US9656968, Compound 38) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2cc(Cl)ccc2F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H17ClFN5O3/c1-10(18(23)28)25-17-9-15(19(24)29)26-20(27-17)11-2-5-13(6-3-11)30-16-8-12(21)4-7-14(16)22/h2-10H,1H3,(H2,23,28)(H2,24,29)(H,25,26,27)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	67	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185916 (US9163008, 5 | US9656968, Compound 5) Show SMILES NC(=O)[C@@H]1CCCN1c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O |r| Show InChI InChI=1S/C22H20FN5O3/c23-14-5-9-16(10-6-14)31-15-7-3-13(4-8-15)22-26-17(20(24)29)12-19(27-22)28-11-1-2-18(28)21(25)30/h3-10,12,18H,1-2,11H2,(H2,24,29)(H2,25,30)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	78	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM186010 (US9163008, 99 | US9656968, Compound 99) Show SMILES NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)-c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C21H17F3N6O3/c22-21(23,24)12-3-6-17(27-10-12)33-13-4-1-11(2-5-13)19-29-15(18(25)31)9-16(30-19)28-14-7-8-26-20(14)32/h1-6,9-10,14H,7-8H2,(H2,25,31)(H,26,32)(H,28,29,30)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	83	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185932 (US9163008, 21 | US9656968, Compound 21) Show SMILES C[C@@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H18FN5O3/c1-11(18(22)27)24-17-10-16(19(23)28)25-20(26-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H2,22,27)(H2,23,28)(H,24,25,26)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	230	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185917 (US9163008, 6 | US9656968, Compound 6) Show SMILES Cn1cnc(C[C@H](Nc2cc(nc(n2)-c2ccc(Oc3ccc(F)cc3)cc2)C(N)=O)C(N)=O)c1 |r| Show InChI InChI=1S/C24H22FN7O3/c1-32-12-16(28-13-32)10-19(22(26)33)29-21-11-20(23(27)34)30-24(31-21)14-2-6-17(7-3-14)35-18-8-4-15(25)5-9-18/h2-9,11-13,19H,10H2,1H3,(H2,26,33)(H2,27,34)(H,29,30,31)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	250	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185964 (US9163008, 53 | US9656968, Compound 53) Show SMILES CS(=O)(=O)N(CC(O)CO)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O Show InChI InChI=1S/C21H21FN4O6S/c1-33(30,31)26(11-15(28)12-27)19-10-18(20(23)29)24-21(25-19)13-2-6-16(7-3-13)32-17-8-4-14(22)5-9-17/h2-10,15,27-28H,11-12H2,1H3,(H2,23,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	270	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185926 (US9163008, 15 | US9656968, Compound 15) Show SMILES COC(=O)[C@@H]1CCCN1c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O |r| Show InChI InChI=1S/C23H21FN4O4/c1-31-23(30)19-3-2-12-28(19)20-13-18(21(25)29)26-22(27-20)14-4-8-16(9-5-14)32-17-10-6-15(24)7-11-17/h4-11,13,19H,2-3,12H2,1H3,(H2,25,29)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	350	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185924 (US9163008, 13 | US9656968, Compound 13) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H17F3N6O3/c1-10(17(24)30)27-15-8-14(18(25)31)28-19(29-15)11-2-5-13(6-3-11)32-16-7-4-12(9-26-16)20(21,22)23/h2-10H,1H3,(H2,24,30)(H2,25,31)(H,27,28,29)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	420	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185913 (US9163008, 2 | US9656968, Compound 2) Show SMILES NC(=O)CNc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O Show InChI InChI=1S/C19H16FN5O3/c20-12-3-7-14(8-4-12)28-13-5-1-11(2-6-13)19-24-15(18(22)27)9-17(25-19)23-10-16(21)26/h1-9H,10H2,(H2,21,26)(H2,22,27)(H,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	590	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185974 (US9163008, 63 | US9656968, Compound 63) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(Cl)cn2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C19H17ClN6O3/c1-10(17(21)27)24-15-8-14(18(22)28)25-19(26-15)11-2-5-13(6-3-11)29-16-7-4-12(20)9-23-16/h2-10H,1H3,(H2,21,27)(H2,22,28)(H,24,25,26)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185946 (US9163008, 35 | US9656968, Compound 35) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(O)=O)C(N)=O |r| Show InChI InChI=1S/C20H17FN4O4/c1-11(18(22)26)23-17-10-16(20(27)28)24-19(25-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H2,22,26)(H,27,28)(H,23,24,25)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185951 (US9163008, 40) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C20H16FN3O5/c1-11(19(25)26)22-17-10-16(20(27)28)23-18(24-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H,25,26)(H,27,28)(H,22,23,24)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma, L.P. US Patent					Assay Description For electrophysiological recordings the external solution was either standard, DMEM supplemented with 10 mM HEPES (pH adjusted to 7.34 with NaOH and ...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185952 (US9163008, 41 | US9656968, Compound 41) Show SMILES NC(=O)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)N1CCOCC1CO Show InChI InChI=1S/C22H21FN4O4/c23-15-3-7-18(8-4-15)31-17-5-1-14(2-6-17)22-25-19(21(24)29)11-20(26-22)27-9-10-30-13-16(27)12-28/h1-8,11,16,28H,9-10,12-13H2,(H2,24,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185953 (US9163008, 42 | US9656968, Compound 42) Show SMILES C[C@@H](CO)Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O |r| Show InChI InChI=1S/C20H19FN4O3/c1-12(11-26)23-18-10-17(19(22)27)24-20(25-18)13-2-6-15(7-3-13)28-16-8-4-14(21)5-9-16/h2-10,12,26H,11H2,1H3,(H2,22,27)(H,23,24,25)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM186004 (US9163008, 93 | US9656968, Compound 93) Show SMILES C[C@H](Oc1cc(nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H16ClFN4O4/c1-10(18(23)27)29-17-9-15(19(24)28)25-20(26-17)11-2-5-13(6-3-11)30-16-7-4-12(21)8-14(16)22/h2-10H,1H3,(H2,23,27)(H2,24,28)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185963 (US9163008, 52 | US9656968, Compound 52) Show SMILES CC1(C)OCC(CN(c2cc(nc(n2)-c2ccc(Oc3ccc(F)cc3)cc2)C(N)=O)S(C)(=O)=O)O1 Show InChI InChI=1S/C24H25FN4O6S/c1-24(2)33-14-19(35-24)13-29(36(3,31)32)21-12-20(22(26)30)27-23(28-21)15-4-8-17(9-5-15)34-18-10-6-16(25)7-11-18/h4-12,19H,13-14H2,1-3H3,(H2,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185928 (US9163008, 17 | US9656968, Compound 17) Show SMILES CCOC(=O)C1(CC1)Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O Show InChI InChI=1S/C23H21FN4O4/c1-2-31-22(30)23(11-12-23)28-19-13-18(20(25)29)26-21(27-19)14-3-7-16(8-4-14)32-17-9-5-15(24)6-10-17/h3-10,13H,2,11-12H2,1H3,(H2,25,29)(H,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185949 (US9163008, 38 | US9656968, Compound 38) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2cc(Cl)ccc2F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H17ClFN5O3/c1-10(18(23)28)25-17-9-15(19(24)29)26-20(27-17)11-2-5-13(6-3-11)30-16-8-12(21)4-7-14(16)22/h2-10H,1H3,(H2,23,28)(H2,24,29)(H,25,26,27)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185955 (US9163008, 44 | US9656968, Compound 44) Show SMILES CC(C)(O)CNc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O Show InChI InChI=1S/C21H21FN4O3/c1-21(2,28)12-24-18-11-17(19(23)27)25-20(26-18)13-3-7-15(8-4-13)29-16-9-5-14(22)6-10-16/h3-11,28H,12H2,1-2H3,(H2,23,27)(H,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185989 (US9163008, 78 | US9656968, Compound 78) Show SMILES NC(=O)[C@@H]1CCCN1c1cc(nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1)C(N)=O |r| Show InChI InChI=1S/C22H19ClFN5O3/c23-13-5-8-18(15(24)10-13)32-14-6-3-12(4-7-14)22-27-16(20(25)30)11-19(28-22)29-9-1-2-17(29)21(26)31/h3-8,10-11,17H,1-2,9H2,(H2,25,30)(H2,26,31)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185986 (US9163008, 75 | US9656968, Compound 75) Show SMILES NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1 |r| Show InChI InChI=1S/C21H17ClFN5O3/c22-12-3-6-17(14(23)9-12)31-13-4-1-11(2-5-13)20-27-16(19(24)29)10-18(28-20)26-15-7-8-25-21(15)30/h1-6,9-10,15H,7-8H2,(H2,24,29)(H,25,30)(H,26,27,28)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185917 (US9163008, 6 | US9656968, Compound 6) Show SMILES Cn1cnc(C[C@H](Nc2cc(nc(n2)-c2ccc(Oc3ccc(F)cc3)cc2)C(N)=O)C(N)=O)c1 |r| Show InChI InChI=1S/C24H22FN7O3/c1-32-12-16(28-13-32)10-19(22(26)33)29-21-11-20(23(27)34)30-24(31-21)14-2-6-17(7-3-14)35-18-8-4-15(25)5-9-18/h2-9,11-13,19H,10H2,1H3,(H2,26,33)(H2,27,34)(H,29,30,31)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185964 (US9163008, 53 | US9656968, Compound 53) Show SMILES CS(=O)(=O)N(CC(O)CO)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O Show InChI InChI=1S/C21H21FN4O6S/c1-33(30,31)26(11-15(28)12-27)19-10-18(20(23)29)24-21(25-19)13-2-6-16(7-3-13)32-17-8-4-14(22)5-9-17/h2-10,15,27-28H,11-12H2,1H3,(H2,23,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185998 (US9163008, 87 | US9656968, Compound 87) Show SMILES NC(=O)[C@@H]1CCCN1c1cc(nc(n1)-c1ccc(Oc2cc(Cl)ccc2F)cc1)C(N)=O |r| Show InChI InChI=1S/C22H19ClFN5O3/c23-13-5-8-15(24)18(10-13)32-14-6-3-12(4-7-14)22-27-16(20(25)30)11-19(28-22)29-9-1-2-17(29)21(26)31/h3-8,10-11,17H,1-2,9H2,(H2,25,30)(H2,26,31)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185954 (US9163008, 43 | US9656968, Compound 43) Show SMILES NC(=O)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)N1CCC[C@H]1CO |r| Show InChI InChI=1S/C22H21FN4O3/c23-15-5-9-18(10-6-15)30-17-7-3-14(4-8-17)22-25-19(21(24)29)12-20(26-22)27-11-1-2-16(27)13-28/h3-10,12,16,28H,1-2,11,13H2,(H2,24,29)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185987 (US9163008, 76 | US9656968, Compound 76) Show SMILES C[C@H](Oc1cc(nc(n1)-c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H17F3N4O5/c1-11(18(25)29)31-17-10-16(19(26)30)27-20(28-17)12-2-4-13(5-3-12)32-14-6-8-15(9-7-14)33-21(22,23)24/h2-11H,1H3,(H2,25,29)(H2,26,30)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185925 (US9163008, 14 | US9656968, Compound 14) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H18F3N5O3/c1-11(18(25)30)27-17-10-16(19(26)31)28-20(29-17)12-2-6-14(7-3-12)32-15-8-4-13(5-9-15)21(22,23)24/h2-11H,1H3,(H2,25,30)(H2,26,31)(H,27,28,29)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185918 (US9163008, 7 | US9656968, Compound 7) Show SMILES NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C21H18FN5O3/c22-13-3-7-15(8-4-13)30-14-5-1-12(2-6-14)20-26-17(19(23)28)11-18(27-20)25-16-9-10-24-21(16)29/h1-8,11,16H,9-10H2,(H2,23,28)(H,24,29)(H,25,26,27)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185960 (US9163008, 49 | US9656968, Compound 49) Show SMILES NC(=O)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)N1CC(O)C(O)C1 |w:25.28,27.30| Show InChI InChI=1S/C21H19FN4O4/c22-13-3-7-15(8-4-13)30-14-5-1-12(2-6-14)21-24-16(20(23)29)9-19(25-21)26-10-17(27)18(28)11-26/h1-9,17-18,27-28H,10-11H2,(H2,23,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM186009 (US9163008, 98 | US9656968, Compound 98) Show SMILES C[C@H](Oc1cc(nc(n1)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H17F3N4O4/c1-11(18(25)29)31-17-10-16(19(26)30)27-20(28-17)12-2-6-14(7-3-12)32-15-8-4-13(5-9-15)21(22,23)24/h2-11H,1H3,(H2,25,29)(H2,26,30)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185959 (US9163008, 48 | US9656968, Compound 48) Show SMILES NC(=O)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)N1CCNCC1CO Show InChI InChI=1S/C22H22FN5O3/c23-15-3-7-18(8-4-15)31-17-5-1-14(2-6-17)22-26-19(21(24)30)11-20(27-22)28-10-9-25-12-16(28)13-29/h1-8,11,16,25,29H,9-10,12-13H2,(H2,24,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185995 (US9163008, 84 | US9656968, Compound 84) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H18F3N5O4/c1-11(18(25)30)27-17-10-16(19(26)31)28-20(29-17)12-2-4-13(5-3-12)32-14-6-8-15(9-7-14)33-21(22,23)24/h2-11H,1H3,(H2,25,30)(H2,26,31)(H,27,28,29)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185921 (US9163008, 10 | US9656968, Compound 10) Show SMILES CC(C)(Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O)C(N)=O Show InChI InChI=1S/C21H20FN5O3/c1-21(2,20(24)29)27-17-11-16(18(23)28)25-19(26-17)12-3-7-14(8-4-12)30-15-9-5-13(22)6-10-15/h3-11H,1-2H3,(H2,23,28)(H2,24,29)(H,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185975 (US9163008, 64 | US9656968, Compound 64) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H17ClFN5O3/c1-10(18(23)28)25-17-9-15(19(24)29)26-20(27-17)11-2-5-13(6-3-11)30-16-7-4-12(21)8-14(16)22/h2-10H,1H3,(H2,23,28)(H2,24,29)(H,25,26,27)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM186002 (US9163008, 91 | US9656968, Compound 91) Show SMILES NC(=O)[C@@H]1CCCN1c1cc(nc(n1)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1)C(N)=O |r| Show InChI InChI=1S/C23H20F3N5O3/c24-23(25,26)14-5-9-16(10-6-14)34-15-7-3-13(4-8-15)22-29-17(20(27)32)12-19(30-22)31-11-1-2-18(31)21(28)33/h3-10,12,18H,1-2,11H2,(H2,27,32)(H2,28,33)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185929 (US9163008, 18 | US9656968, Compound 18) Show SMILES COC(=O)C(C)(C)Nc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O Show InChI InChI=1S/C22H21FN4O4/c1-22(2,21(29)30-3)27-18-12-17(19(24)28)25-20(26-18)13-4-8-15(9-5-13)31-16-10-6-14(23)7-11-16/h4-12H,1-3H3,(H2,24,28)(H,25,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185996 (US9163008, 85 | US9656968, Compound 85) Show SMILES C[C@H](Nc1cc(nc(n1)-c1ccc(Oc2ccc3OCOc3c2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H19N5O5/c1-11(19(22)27)24-18-9-15(20(23)28)25-21(26-18)12-2-4-13(5-3-12)31-14-6-7-16-17(8-14)30-10-29-16/h2-9,11H,10H2,1H3,(H2,22,27)(H2,23,28)(H,24,25,26)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185967 (US9163008, 56 | US9656968, Compound 56) Show SMILES C[C@H](Oc1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C20H17FN4O4/c1-11(18(22)26)28-17-10-16(19(23)27)24-20(25-17)12-2-6-14(7-3-12)29-15-8-4-13(21)5-9-15/h2-11H,1H3,(H2,22,26)(H2,23,27)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185956 (US9163008, 45 | US9656968, Compound 45) Show SMILES NC(=O)c1cc(NCC2(O)CCCCC2)nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C24H25FN4O3/c25-17-6-10-19(11-7-17)32-18-8-4-16(5-9-18)23-28-20(22(26)30)14-21(29-23)27-15-24(31)12-2-1-3-13-24/h4-11,14,31H,1-3,12-13,15H2,(H2,26,30)(H,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185931 (US9163008, 20 | US9656968, Compound 20) Show SMILES C[C@H](N(C)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C21H20FN5O3/c1-12(19(23)28)27(2)18-11-17(20(24)29)25-21(26-18)13-3-7-15(8-4-13)30-16-9-5-14(22)6-10-16/h3-12H,1-2H3,(H2,23,28)(H2,24,29)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM186013 (US9163008, 102 | US9656968, Compound 102) Show SMILES NC(=O)c1cc(O[C@H]2CCNC2=O)nc(n1)C1=CCC(CC1)Oc1ccc(cc1)C(F)(F)F |r,t:18| Show InChI InChI=1S/C22H21F3N4O4/c23-22(24,25)13-3-7-15(8-4-13)32-14-5-1-12(2-6-14)20-28-16(19(26)30)11-18(29-20)33-17-9-10-27-21(17)31/h1,3-4,7-8,11,14,17H,2,5-6,9-10H2,(H2,26,30)(H,27,31)/t14?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185985 (US9163008, 74 | US9656968, Compound 74) Show SMILES NC(=O)C1CN(CCN1)c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O Show InChI InChI=1S/C22H21FN6O3/c23-14-3-7-16(8-4-14)32-15-5-1-13(2-6-15)22-27-17(20(24)30)11-19(28-22)29-10-9-26-18(12-29)21(25)31/h1-8,11,18,26H,9-10,12H2,(H2,24,30)(H2,25,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185916 (US9163008, 5 | US9656968, Compound 5) Show SMILES NC(=O)[C@@H]1CCCN1c1cc(nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O |r| Show InChI InChI=1S/C22H20FN5O3/c23-14-5-9-16(10-6-14)31-15-7-3-13(4-8-15)22-26-17(20(24)29)12-19(27-22)28-11-1-2-18(28)21(25)30/h3-10,12,18H,1-2,11H2,(H2,24,29)(H2,25,30)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 122 total )  |  Next  |  Last  >>

Jump to: