Compile Data Set for Download or QSAR

Found 68 hits of ki for UniProtKB: P62813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26263 (Anexate | CHEMBL407 | FLUMAZENIL | Ro15-1788 | Rom...) Show SMILES CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(F)ccc-21 Show InChI InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heidelberg Curated by ChEMBL					Assay Description Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells				J Med Chem 37: 4576-80 (1995) BindingDB Entry DOI: 10.7270/Q2154HPB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50035527 (3-Methyl-9H-beta-carboline | CHEMBL344859) Show SMILES Cc1cc2c(c[nH]1)nc1ccccc21 Show InChI InChI=1S/C12H10N2/c1-8-6-10-9-4-2-3-5-11(9)14-12(10)7-13-8/h2-7,13H,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heidelberg Curated by ChEMBL					Assay Description Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells				J Med Chem 37: 4576-80 (1995) BindingDB Entry DOI: 10.7270/Q2154HPB
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165326 (8-Chloro-2-phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta...) Show SMILES Clc1ccc2[nH]c(=O)n3nc(-c4ccccc4)c(=O)n3c2c1 Show InChI InChI=1S/C15H9ClN4O2/c16-10-6-7-11-12(8-10)19-14(21)13(9-4-2-1-3-5-9)18-20(19)15(22)17-11/h1-8H,(H,17,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha1-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165329 (8-Chloro-2-(4-methoxy-phenyl)-5H-3,3a,5,9b-tetraaz...) Show SMILES COc1ccc(cc1)-c1nn2n(c3cc(Cl)ccc3[nH]c2=O)c1=O Show InChI InChI=1S/C16H11ClN4O3/c1-24-11-5-2-9(3-6-11)14-15(22)20-13-8-10(17)4-7-12(13)18-16(23)21(20)19-14/h2-8H,1H3,(H,18,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha1-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50001478 (9H-beta-Carboline-3-carboxylic acid methyl ester |...) Show SMILES COC(=O)c1cc2c(c[nH]1)nc1ccccc21 Show InChI InChI=1S/C13H10N2O2/c1-17-13(16)11-6-9-8-4-2-3-5-10(8)15-12(9)7-14-11/h2-7,14H,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heidelberg Curated by ChEMBL					Assay Description Binding affinity for mutant rat GABA-A receptor alpha-1-(arg)-beta-2-gamma-2 subunits expressed in HEK293 cells				J Med Chem 37: 4576-80 (1995) BindingDB Entry DOI: 10.7270/Q2154HPB
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50205615 (3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine...) Show SMILES CCOc1ccc2n[n+]([O-])c3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O2/c1-2-18-7-3-4-9-10(5-7)15-11(16(17)14-9)8(12)6-13-15/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122013 (8-Chloro-5-oxy-benzo[e]pyrazolo[5,1-c][1,2,4]triaz...) Show SMILES [O-][n+]1nc2c(cnn2c2cc(Cl)ccc12)C(=O)OCc1cccs1 Show InChI InChI=1S/C15H9ClN4O3S/c16-9-3-4-12-13(6-9)19-14(18-20(12)22)11(7-17-19)15(21)23-8-10-2-1-5-24-10/h1-7H,8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165325 (2-(4-Methoxy-phenyl)-5H-3,3a,5,9b-tetraaza-cyclope...) Show SMILES COc1ccc(cc1)-c1nn2n(c3ccccc3[nH]c2=O)c1=O Show InChI InChI=1S/C16H12N4O3/c1-23-11-8-6-10(7-9-11)14-15(21)19-13-5-3-2-4-12(13)17-16(22)20(19)18-14/h2-9H,1H3,(H,17,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha1-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50205622 (8-ethoxy-3-iodo-benzo[e]pyrazolo[5,1-c][1,2,4]tria...) Show SMILES CCOc1ccc2[n+]([O-])nc3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O2/c1-2-18-7-3-4-9-10(5-7)15-11(14-16(9)17)8(12)6-13-15/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50078032 (8-Chloro-3-thiophen-3-yl-benzo[e]pyrazolo[5,1-c][1...) Show SMILES [O-][n+]1nc2c(cnn2c2cc(Cl)ccc12)-c1ccsc1 Show InChI InChI=1S/C13H7ClN4OS/c14-9-1-2-11-12(5-9)17-13(16-18(11)19)10(6-15-17)8-3-4-20-7-8/h1-7H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50461578 (CHEMBL4227819) Show SMILES FC(F)(F)c1cccc(c1)-c1cnn2c1[nH]nc(-c1cc[nH]n1)c2=O Show InChI InChI=1S/C15H9F3N6O/c16-15(17,18)9-3-1-2-8(6-9)10-7-20-24-13(10)23-22-12(14(24)25)11-4-5-19-21-11/h1-7,23H,(H,19,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from recombinant rat GABAAalpha1/beta2/gamma2 receptor after 90 mins by liquid scintillation counting method				Bioorg Med Chem 26: 2475-2487 (2018) Article DOI: 10.1016/j.bmc.2018.04.011 BindingDB Entry DOI: 10.7270/Q2D79F10
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122842 (3-Pyridin-2-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccccn1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-11(10-4-6-21-9-10)7-17-14-12(8-18-19(14)15)13-3-1-2-5-16-13/h1-9,18H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50461573 (CHEMBL4227473) Show SMILES O=c1c(n[nH]c2c(cnn12)-c1ccccn1)-c1cc[nH]n1 Show InChI InChI=1S/C13H9N7O/c21-13-11(10-4-6-15-17-10)18-19-12-8(7-16-20(12)13)9-3-1-2-5-14-9/h1-7,19H,(H,15,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from recombinant rat GABAAalpha1/beta2/gamma2 receptor after 90 mins by liquid scintillation counting method				Bioorg Med Chem 26: 2475-2487 (2018) Article DOI: 10.1016/j.bmc.2018.04.011 BindingDB Entry DOI: 10.7270/Q2D79F10
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha1-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50185264 (CHEMBL204841 | N-((1H-pyrrol-3-yl)methyl)-2-(5-nit...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3cc[nH]c3)c2c1 Show InChI InChI=1S/C15H12N4O4/c20-14(15(21)18-7-9-3-4-16-6-9)12-8-17-13-2-1-10(19(22)23)5-11(12)13/h1-6,8,16-17H,7H2,(H,18,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha1 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122843 (6-Thiophen-3-yl-3-(3-trifluoromethyl-phenyl)-4H-py...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H10F3N3OS/c18-17(19,20)12-3-1-2-10(6-12)13-8-22-23-15(13)21-7-14(16(23)24)11-4-5-25-9-11/h1-9,22H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122840 (3-(3-Bromo-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1,5...) Show SMILES Brc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C16H10BrN3OS/c17-12-3-1-2-10(6-12)13-8-19-20-15(13)18-7-14(16(20)21)11-4-5-22-9-11/h1-9,19H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50205616 (3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine...) Show SMILES CCOc1ccc2nnc3c(I)cnn3c2c1 Show InChI InChI=1S/C11H9IN4O/c1-2-17-7-3-4-9-10(5-7)16-11(15-14-9)8(12)6-13-16/h3-6H,2H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat recombinant GABAalpha1beta2gamma2 receptor expressed in HEK293 cells				Bioorg Med Chem 15: 2573-86 (2007) Article DOI: 10.1016/j.bmc.2007.01.053 BindingDB Entry DOI: 10.7270/Q2ZP45TJ
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50101427 ((R)-2-(5-nitro-1H-indol-3-yl)-2-oxo-N-(1-phenyleth...) Show SMILES C[C@@H](NC(=O)C(=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1ccccc1 |r| Show InChI InChI=1S/C18H15N3O4/c1-11(12-5-3-2-4-6-12)20-18(23)17(22)15-10-19-16-8-7-13(21(24)25)9-14(15)16/h2-11,19H,1H3,(H,20,23)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50001478 (9H-beta-Carboline-3-carboxylic acid methyl ester |...) Show SMILES COC(=O)c1cc2c(c[nH]1)nc1ccccc21 Show InChI InChI=1S/C13H10N2O2/c1-17-13(16)11-6-9-8-4-2-3-5-10(8)15-12(9)7-14-11/h2-7,14H,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heidelberg Curated by ChEMBL					Assay Description Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells				J Med Chem 37: 4576-80 (1995) BindingDB Entry DOI: 10.7270/Q2154HPB
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206936 (CHEMBL375367 | N-isopropyl-2-(5-nitro-1H-indol-3-y...) Show SMILES CC(C)NC(=O)C(=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C13H13N3O4/c1-7(2)15-13(18)12(17)10-6-14-11-4-3-8(16(19)20)5-9(10)11/h3-7,14H,1-2H3,(H,15,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50101429 (2-(1H-Indol-3-yl)-N-(4-nitro-benzyl)-2-oxo-acetami...) Show SMILES [O-][N+](=O)c1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C17H13N3O4/c21-16(14-10-18-15-4-2-1-3-13(14)15)17(22)19-9-11-5-7-12(8-6-11)20(23)24/h1-8,10,18H,9H2,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heidelberg Curated by ChEMBL					Assay Description Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells				J Med Chem 37: 4576-80 (1995) BindingDB Entry DOI: 10.7270/Q2154HPB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206941 (CHEMBL376508 | N-(4-bromobenzyl)-2-(1H-indol-3-yl)...) Show SMILES Brc1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C17H13BrN2O2/c18-12-7-5-11(6-8-12)9-20-17(22)16(21)14-10-19-15-4-2-1-3-13(14)15/h1-8,10,19H,9H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heidelberg Curated by ChEMBL					Assay Description Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cells				J Med Chem 37: 4576-80 (1995) BindingDB Entry DOI: 10.7270/Q2154HPB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50370710 (CHEMBL1162923) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3ccco3)c2c1 Show InChI InChI=1S/C15H11N3O5/c19-14(15(20)17-7-10-2-1-5-23-10)12-8-16-13-4-3-9(18(21)22)6-11(12)13/h1-6,8,16H,7H2,(H,17,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha1 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50461577 (CHEMBL4228914) Show SMILES Brc1cccc(c1)-c1cnn2c1[nH]nc(-c1cc[nH]n1)c2=O Show InChI InChI=1S/C14H9BrN6O/c15-9-3-1-2-8(6-9)10-7-17-21-13(10)20-19-12(14(21)22)11-4-5-16-18-11/h1-7,20H,(H,16,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from recombinant rat GABAAalpha1/beta2/gamma2 receptor after 90 mins by liquid scintillation counting method				Bioorg Med Chem 26: 2475-2487 (2018) Article DOI: 10.1016/j.bmc.2018.04.011 BindingDB Entry DOI: 10.7270/Q2D79F10
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122841 (3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccsc1)-c1ccsc1 Show InChI InChI=1S/C14H9N3OS2/c18-14-12(10-2-4-20-8-10)5-15-13-11(6-16-17(13)14)9-1-3-19-7-9/h1-8,16H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122847 (3-Pyridin-3-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccnc1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-13(11-3-5-21-9-11)7-17-14-12(8-18-19(14)15)10-2-1-4-16-6-10/h1-9,18H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50066949 ((1H-Indol-3-yl)-oxo-acetic acid N'-(4-nitro-phenyl...) Show SMILES [O-][N+](=O)c1ccc(NNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C16H12N4O4/c21-15(13-9-17-14-4-2-1-3-12(13)14)16(22)19-18-10-5-7-11(8-6-10)20(23)24/h1-9,17-18H,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	26.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-15-1788 from rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 45: 5710-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0SWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	26.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206939 (CHEMBL223707 | N-(p-methylbenzyl)-5-nitroindol-3-y...) Show SMILES Cc1ccc(CNC(=O)C(=O)c2c[nH]c3ccc(cc23)[N+]([O-])=O)cc1 Show InChI InChI=1S/C18H15N3O4/c1-11-2-4-12(5-3-11)9-20-18(23)17(22)15-10-19-16-7-6-13(21(24)25)8-14(15)16/h2-8,10,19H,9H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50055247 (CHEMBL75306 | N-(4-Methoxy-benzyl)-2-(5-nitro-1H-i...) Show SMILES COc1ccc(CNC(=O)C(=O)c2c[nH]c3ccc(cc23)[N+]([O-])=O)cc1 Show InChI InChI=1S/C18H15N3O5/c1-26-13-5-2-11(3-6-13)9-20-18(23)17(22)15-10-19-16-7-4-12(21(24)25)8-14(15)16/h2-8,10,19H,9H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122845 (3-(3-Methoxy-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1...) Show SMILES COc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H13N3O2S/c1-22-13-4-2-3-11(7-13)14-9-19-20-16(14)18-8-15(17(20)21)12-5-6-23-10-12/h2-10,19H,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122848 (3-Naphthalen-1-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccc2ccccc12)-c1ccsc1 Show InChI InChI=1S/C20H13N3OS/c24-20-17(14-8-9-25-12-14)10-21-19-18(11-22-23(19)20)16-7-3-5-13-4-1-2-6-15(13)16/h1-12,22H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha1-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil specific binding at rat GABA-A alpha1-beta2-gamma2 receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha1 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha1-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50461572 (CHEMBL4225762) Show SMILES O=c1c(n[nH]c2c(cnn12)-c1cccnc1)-c1cc[nH]n1 Show InChI InChI=1S/C13H9N7O/c21-13-11(10-3-5-15-17-10)18-19-12-9(7-16-20(12)13)8-2-1-4-14-6-8/h1-7,19H,(H,15,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from recombinant rat GABAAalpha1/beta2/gamma2 receptor after 90 mins by liquid scintillation counting method				Bioorg Med Chem 26: 2475-2487 (2018) Article DOI: 10.1016/j.bmc.2018.04.011 BindingDB Entry DOI: 10.7270/Q2D79F10
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50185269 (CHEMBL203629 | N-(furan-3-ylmethyl)-2-(5-nitro-1H-...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3ccoc3)c2c1 Show InChI InChI=1S/C15H11N3O5/c19-14(15(20)17-6-9-3-4-23-8-9)12-7-16-13-2-1-10(18(21)22)5-11(12)13/h1-5,7-8,16H,6H2,(H,17,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha1 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50055261 (CHEMBL75307 | N-Benzyl-2-(5-nitro-1H-indol-3-yl)-2...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3ccccc3)c2c1 Show InChI InChI=1S/C17H13N3O4/c21-16(17(22)19-9-11-4-2-1-3-5-11)14-10-18-15-7-6-12(20(23)24)8-13(14)15/h1-8,10,18H,9H2,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha1beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50461576 (CHEMBL4228076) Show SMILES Clc1cccc(c1)-c1cnn2c1[nH]nc(-c1cc[nH]n1)c2=O Show InChI InChI=1S/C14H9ClN6O/c15-9-3-1-2-8(6-9)10-7-17-21-13(10)20-19-12(14(21)22)11-4-5-16-18-11/h1-7,20H,(H,16,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from recombinant rat GABAAalpha1/beta2/gamma2 receptor after 90 mins by liquid scintillation counting method				Bioorg Med Chem 26: 2475-2487 (2018) Article DOI: 10.1016/j.bmc.2018.04.011 BindingDB Entry DOI: 10.7270/Q2D79F10
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50185273 (CHEMBL383656 | N-((1H-pyrrol-2-yl)methyl)-2-(5-nit...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3ccc[nH]3)c2c1 Show InChI InChI=1S/C15H12N4O4/c20-14(15(21)18-7-9-2-1-5-16-9)12-8-17-13-4-3-10(19(22)23)6-11(12)13/h1-6,8,16-17H,7H2,(H,18,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha1 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50461571 (CHEMBL4225681) Show SMILES Fc1ccc(cc1)-c1cnn2c1[nH]nc(-c1cc[nH]n1)c2=O Show InChI InChI=1S/C14H9FN6O/c15-9-3-1-8(2-4-9)10-7-17-21-13(10)20-19-12(14(21)22)11-5-6-16-18-11/h1-7,20H,(H,16,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from recombinant rat GABAAalpha1/beta2/gamma2 receptor after 90 mins by liquid scintillation counting method				Bioorg Med Chem 26: 2475-2487 (2018) Article DOI: 10.1016/j.bmc.2018.04.011 BindingDB Entry DOI: 10.7270/Q2D79F10
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50461579 (CHEMBL4227285) Show SMILES Fc1cccc(c1)-c1cnn2c1[nH]nc(-c1cc[nH]n1)c2=O Show InChI InChI=1S/C14H9FN6O/c15-9-3-1-2-8(6-9)10-7-17-21-13(10)20-19-12(14(21)22)11-4-5-16-18-11/h1-7,20H,(H,16,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from recombinant rat GABAAalpha1/beta2/gamma2 receptor after 90 mins by liquid scintillation counting method				Bioorg Med Chem 26: 2475-2487 (2018) Article DOI: 10.1016/j.bmc.2018.04.011 BindingDB Entry DOI: 10.7270/Q2D79F10
					More data for this Ligand-Target Pair

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