Compile Data Set for Download or QSAR

Found 15 hits of ki for UniProtKB: P21917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50005118 ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC Show InChI InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-Spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes (using L-tartrate salt of authentic rac...				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50005118 ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC Show InChI InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50228777 (CHEMBL80127) Show SMILES [H][C@@]1(CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC)CCCN1CCC Show InChI InChI=1S/C16H22Cl2N2O3/c1-3-6-20-7-4-5-10(20)9-19-16(22)13-14(21)11(17)8-12(18)15(13)23-2/h8,10,21H,3-7,9H2,1-2H3,(H,19,22)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50228772 (CHEMBL418922) Show SMILES [H][C@@]1(CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC)CCCN1CCCC Show InChI InChI=1S/C17H24Cl2N2O3/c1-3-4-7-21-8-5-6-11(21)10-20-17(23)14-15(22)12(18)9-13(19)16(14)24-2/h9,11,22H,3-8,10H2,1-2H3,(H,20,23)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50228774 (CHEMBL80126) Show SMILES [H][C@@]1(CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC)CCCN1CCCCF Show InChI InChI=1S/C17H23Cl2FN2O3/c1-25-16-13(19)9-12(18)15(23)14(16)17(24)21-10-11-5-4-8-22(11)7-3-2-6-20/h9,11,23H,2-8,10H2,1H3,(H,21,24)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50134526 (2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...) Show SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1 Show InChI InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Ability to inhibit the binding of human DP receptor to PGD-2				Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50228776 (CHEMBL81778) Show SMILES [H][C@@]1(CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC)CCCN1CCCF Show InChI InChI=1S/C16H21Cl2FN2O3/c1-24-15-12(18)8-11(17)14(22)13(15)16(23)20-9-10-4-2-6-21(10)7-3-5-19/h8,10,22H,2-7,9H2,1H3,(H,20,23)/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50228771 (CHEMBL312602) Show SMILES [H][C@@]1(CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC)CCCN1CCF Show InChI InChI=1S/C15H19Cl2FN2O3/c1-23-14-11(17)7-10(16)13(21)12(14)15(22)19-8-9-3-2-5-20(9)6-4-18/h7,9,21H,2-6,8H2,1H3,(H,19,22)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	159	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50159788 (CHEMBL3786973) Show SMILES CCN\C(=N/S(=O)(=O)c1ccc(N)cc1)N1CC2(CCCC2)C=N1 |c:24| Show InChI InChI=1S/C16H23N5O2S/c1-2-18-15(21-12-16(11-19-21)9-3-4-10-16)20-24(22,23)14-7-5-13(17)6-8-14/h5-8,11H,2-4,9-10,12,17H2,1H3,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Healthcare Products B.V. Curated by ChEMBL					Assay Description Binding affinity to dopamine receptor (unknown origin)				Bioorg Med Chem Lett 26: 1605-11 (2016) Article DOI: 10.1016/j.bmcl.2016.02.001 BindingDB Entry DOI: 10.7270/Q2JS9SBX
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50187377 (CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Binding affinity to dopamine receptor by radioligand binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50228775 (CHEMBL77448) Show SMILES [H][C@@]1(CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC)CCCN1CCC(C)F Show InChI InChI=1S/C17H23Cl2FN2O3/c1-10(20)5-7-22-6-3-4-11(22)9-21-17(24)14-15(23)12(18)8-13(19)16(14)25-2/h8,10-11,23H,3-7,9H2,1-2H3,(H,21,24)/t10?,11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50228773 (CHEMBL2021339) Show SMILES [H][C@]1(CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC)CCCN1CCC(C)F |r| Show InChI InChI=1S/C17H23Cl2FN2O3/c1-10(20)5-7-22-6-3-4-11(22)9-21-17(24)14-15(23)12(18)8-13(19)16(14)25-2/h8,10-11,23H,3-7,9H2,1-2H3,(H,21,24)/t10?,11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description In vitro inhibition of [3H]spiperone binding to Dopamine receptor D2 in Macaca nemestrina striatal membranes				J Med Chem 33: 2430-7 (1990) BindingDB Entry DOI: 10.7270/Q23J3BXF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards cloned rat 5-hydroxytryptamine 2A receptor by [3H]-ketanserin displacement.				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards cloned rat 5-hydroxytryptamine 2A receptor by [3H]-ketanserin displacement.				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Homo sapiens (Human))	BDBM50136493 (1-Methyl-4,9-dihydro-3H-beta-carboline | 1-methyl-...) Show SMILES CC1=NCCc2c1[nH]c1ccccc21 |t:1| Show InChI InChI=1S/C12H12N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-5,14H,6-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards cloned rat Inhibition of binding towards 5-hydroxytryptamine 2A receptor at 100 nM concentration was determined using [3H]-D...				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair