Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM25392 (4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cells | J Med Chem 34: 1063-8 (1991) BindingDB Entry DOI: 10.7270/Q2765D9R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007476 (4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cells | J Med Chem 34: 1063-8 (1991) BindingDB Entry DOI: 10.7270/Q2765D9R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007477 (4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Activity was evaluated by measuring the inhibition of isolated hog H+/K+ ATPase | J Med Chem 34: 1063-8 (1991) BindingDB Entry DOI: 10.7270/Q2765D9R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019059 ((+/-)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-be...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Agonistic potency at beta adrenergic receptor for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cells | J Med Chem 31: 1972-7 (1988) BindingDB Entry DOI: 10.7270/Q2V69K54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019059 ((+/-)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-be...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50029051 ((-)-arterenol | (-)-noradrenaline | (-)-norepineph...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019060 ((+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50029050 ((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | n/a | n/a | 230 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50029050 ((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | n/a | n/a | 230 | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Agonistic potency at alpha-1 adrenergic receptor for the amine-induced increase of phosphatidylinositol breakdown in synaptoneurosomes from guinea pi... | J Med Chem 31: 1972-7 (1988) BindingDB Entry DOI: 10.7270/Q2V69K54 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM35234 (DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019057 ((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.50E+3 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019057 ((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.50E+3 | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Agonistic potency at beta adrenergic receptor for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cells | J Med Chem 31: 1972-7 (1988) BindingDB Entry DOI: 10.7270/Q2V69K54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50042998 (5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros... | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019060 ((+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50042998 (5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM35234 (DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros... | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019060 ((+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros... | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019061 ((+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019061 ((+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membrane | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50042997 (4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor | J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1/Beta-2/Beta-3 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50019061 ((+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros... | J Med Chem 22: 1493-7 (1979) Article DOI: 10.1021/jm00198a012 BindingDB Entry DOI: 10.7270/Q2RV0RQK | |||||||||||
More data for this Ligand-Target Pair |