Found 6 hits of ic50 for monomerid = 50146460 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50146460
(CHEMBL3763688)Show InChI InChI=1S/C7H8INO.ClH/c8-7-3-1-6(2-4-7)5-10-9;/h1-4H,5,9H2;1H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College
Curated by ChEMBL
| Assay Description Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning... |
Eur J Med Chem 108: 564-76 (2016)
Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50146460
(CHEMBL3763688)Show InChI InChI=1S/C7H8INO.ClH/c8-7-3-1-6(2-4-7)5-10-9;/h1-4H,5,9H2;1H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College
Curated by ChEMBL
| Assay Description Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 3-fold serial dilution beginning... |
Eur J Med Chem 108: 564-76 (2016)
Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50146460
(CHEMBL3763688)Show InChI InChI=1S/C7H8INO.ClH/c8-7-3-1-6(2-4-7)5-10-9;/h1-4H,5,9H2;1H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College
Curated by ChEMBL
| Assay Description Inhibition of doxycycline-induced human IDO1 expressed in Trex cells assessed as reduction in kynurenine production treated with 5-fold serial diluti... |
Eur J Med Chem 108: 564-76 (2016)
Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50146460
(CHEMBL3763688)Show InChI InChI=1S/C7H8INO.ClH/c8-7-3-1-6(2-4-7)5-10-9;/h1-4H,5,9H2;1H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College
Curated by ChEMBL
| Assay Description Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade... |
Eur J Med Chem 108: 564-76 (2016)
Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T |
More data for this Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50146460
(CHEMBL3763688)Show InChI InChI=1S/C7H8INO.ClH/c8-7-3-1-6(2-4-7)5-10-9;/h1-4H,5,9H2;1H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College
Curated by ChEMBL
| Assay Description Inhibition of CYP3A4 (unknown origin) |
Eur J Med Chem 108: 564-76 (2016)
Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T |
More data for this Ligand-Target Pair | |
Catalase
(Homo sapiens (Human)) | BDBM50146460
(CHEMBL3763688)Show InChI InChI=1S/C7H8INO.ClH/c8-7-3-1-6(2-4-7)5-10-9;/h1-4H,5,9H2;1H | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bryn Mawr College
Curated by ChEMBL
| Assay Description Inhibition of catalase (unknown origin) using hydrogen peroxide as substrate |
Eur J Med Chem 108: 564-76 (2016)
Article DOI: 10.1016/j.ejmech.2015.12.028 BindingDB Entry DOI: 10.7270/Q26Q203T |
More data for this Ligand-Target Pair | |