BindingDB PrimarySearch

Found 4 hits of ic50 for monomerid = 50156669
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human))	BDBM50156669 (4,5,6,7-TETRABROMO-BENZIMIDAZOLE \| 4,5,6,7-tetrabr...) Show SMILES Brc1c(Br)c(Br)c2[nH]cnc2c1Br Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
University of Western Ontario					Assay Description To determine the IC50 value of each inhibitor, reactions were initiated by addition of 154 pM NQO2 to a reaction buffer containing 150 μM SCDP a...				Biochemistry 54: 47-59 (2015) Article DOI: 10.1021/bi500959t BindingDB Entry DOI: 10.7270/Q2BV7FC9
University of Western Ontario					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50156669 (4,5,6,7-TETRABROMO-BENZIMIDAZOLE \| 4,5,6,7-tetrabr...) Show SMILES Brc1c(Br)c(Br)c2[nH]cnc2c1Br Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Displacement of 5-TAMRA-labeled ARC-1530 from CK2alpha (unknown origin) (1 to 335 residues) after 15 to 60 mins by luminescence assay				Bioorg Med Chem 26: 5062-5068 (2018) Article DOI: 10.1016/j.bmc.2018.09.003 BindingDB Entry DOI: 10.7270/Q26112V7
University of Tartu Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50156669 (4,5,6,7-TETRABROMO-BENZIMIDAZOLE \| 4,5,6,7-tetrabr...) Show SMILES Brc1c(Br)c(Br)c2[nH]cnc2c1Br Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biochemistry and Biophysics Curated by ChEMBL					Assay Description Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scin...				Bioorg Med Chem 17: 1573-8 (2009) Article DOI: 10.1016/j.bmc.2008.12.071 BindingDB Entry DOI: 10.7270/Q23J3CVZ
Institute of Biochemistry and Biophysics Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50156669 (4,5,6,7-TETRABROMO-BENZIMIDAZOLE \| 4,5,6,7-tetrabr...) Show SMILES Brc1c(Br)c(Br)c2[nH]cnc2c1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin)				J Med Chem 61: 9791-9810 (2018) Article DOI: 10.1021/acs.jmedchem.8b00185 BindingDB Entry DOI: 10.7270/Q2H41V3Q
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair