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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phospholipase D (Streptomyces chromofuscus) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | UniProtKB/SwissProt GoogleScholar AffyNet  | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of RIP2 in the presence of 100uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Casein kinase I isoform delta (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of CK1delta in the presence of 20uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 8 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of JNK-M108A in the presence of 20uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proto-oncogene tyrosine-protein kinase Src (Gallus gallus (Chicken)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Src in the presence of 50uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Phospholipase D2 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | 37 |
University of Massachusetts Boston | Assay Description PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions... | Chem Biol Drug Des 84: 270-81 (2014) Article DOI: 10.1111/cbdd.12319 BindingDB Entry DOI: 10.7270/Q2HT2N05 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phospholipase D (Streptomyces sp. PMF) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 385 | n/a | n/a | n/a | n/a | n/a | 37 |
University of Massachusetts Boston | Assay Description PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions... | Chem Biol Drug Des 84: 270-81 (2014) Article DOI: 10.1111/cbdd.12319 BindingDB Entry DOI: 10.7270/Q2HT2N05 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Phospholipase D1 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 426 | n/a | n/a | n/a | n/a | n/a | 37 |
University of Massachusetts Boston | Assay Description PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions... | Chem Biol Drug Des 84: 270-81 (2014) Article DOI: 10.1111/cbdd.12319 BindingDB Entry DOI: 10.7270/Q2HT2N05 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of Fyn | Proc Natl Acad Sci USA 104: 20523-8 (2007) Checked by Author Article DOI: 10.1073/pnas.0708800104 BindingDB Entry DOI: 10.7270/Q2DB82RH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of wild type c-Fyn | Nat Chem Biol 1: 130-42 (2006) Article DOI: 10.1038/nchembio0805-130 BindingDB Entry DOI: 10.7270/Q2RN383S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of wild type c-Abl | Nat Chem Biol 1: 130-42 (2006) Article DOI: 10.1038/nchembio0805-130 BindingDB Entry DOI: 10.7270/Q2RN383S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 8 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of JNK-M108G in the presence of 20uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proto-oncogene tyrosine-protein kinase LCK (Mus musculus) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of Lck in the presence of 50uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of PKD1 in the presence of 50uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K077GQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO US Patent | Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... | US Patent US10544104 (2020) BindingDB Entry DOI: 10.7270/Q2D79DSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center for Commercialization US Patent | Assay Description Inhibition of human tyrosine kinases. | US Patent US9765037 (2017) BindingDB Entry DOI: 10.7270/Q2B56MVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calmodulin-domain protein kinase 1 (Toxoplasma gondii) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington. Curated by ChEMBL | Assay Description Inhibition of Toxoplasma gondii recombinant N-terminal hexahistidine tagged CDPK1 expressed in Escherichia coli using syntide-2 as substrate after 90... | ACS Med Chem Lett 1: 331-335 (2011) Article DOI: 10.1021/ml100096t BindingDB Entry DOI: 10.7270/Q2JW8FV5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calmodulin-domain protein kinase 1 (Toxoplasma gondii) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center for Commercialization US Patent | Assay Description Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a... | US Patent US9765037 (2017) BindingDB Entry DOI: 10.7270/Q2B56MVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cGMP-dependent protein kinase () | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K077GQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calmodulin-domain protein kinase 1 (Toxoplasma gondii) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO US Patent | Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... | US Patent US10544104 (2020) BindingDB Entry DOI: 10.7270/Q2D79DSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase CSK (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Inhibition of CSK in the presence of 20uM ATP | Biochem J 408: 297-315 (2007) Article DOI: 10.1042/BJ20070797 BindingDB Entry DOI: 10.7270/Q27082B4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands (Cryptosporidium parvum (strain Iowa II)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K077GQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calmodulin-domain protein kinase 1, putative (Cryptosporidium parvum (strain Iowa II)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO US Patent | Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... | US Patent US10544104 (2020) BindingDB Entry DOI: 10.7270/Q2D79DSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcium-dependent protein kinase 1 (Cryptosporidium parvum) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center for Commercialization US Patent | Assay Description Two types of enzyme assays were developed to follow TgCDPK1 activity, a radiometric scintillation proximity assay measured the labeled γ-phospha... | US Patent US9765037 (2017) BindingDB Entry DOI: 10.7270/Q2B56MVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of wild type CDK2 | Nat Chem Biol 1: 130-42 (2006) Article DOI: 10.1038/nchembio0805-130 BindingDB Entry DOI: 10.7270/Q2RN383S | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center for Commercialization US Patent | Assay Description Inhibition of human tyrosine kinases. | US Patent US9765037 (2017) BindingDB Entry DOI: 10.7270/Q2B56MVC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO US Patent | Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... | US Patent US10544104 (2020) BindingDB Entry DOI: 10.7270/Q2D79DSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K077GQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C iota type (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibition of human PKCiota | J Biol Chem 282: 33052-63 (2007) Article DOI: 10.1074/jbc.M707233200 BindingDB Entry DOI: 10.7270/Q2TB16NW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C delta type (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibition of human PKCdelta | J Biol Chem 282: 33052-63 (2007) Article DOI: 10.1074/jbc.M707233200 BindingDB Entry DOI: 10.7270/Q2TB16NW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C gamma type (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibition of human PKCgamma | J Biol Chem 282: 33052-63 (2007) Article DOI: 10.1074/jbc.M707233200 BindingDB Entry DOI: 10.7270/Q2TB16NW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C epsilon type (Homo sapiens (Human)) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California-San Francisco Curated by ChEMBL | Assay Description Inhibition of human PKCepsilon | J Biol Chem 282: 33052-63 (2007) Article DOI: 10.1074/jbc.M707233200 BindingDB Entry DOI: 10.7270/Q2TB16NW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
