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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Inc. Curated by ChEMBL | Assay Description Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated... | ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Therapeutics Curated by ChEMBL | Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo... | J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr... | Bioorg Med Chem Lett 28: 3113-3118 (2018) Article DOI: 10.1016/j.bmcl.2018.07.001 BindingDB Entry DOI: 10.7270/Q28P6366 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Inc. Curated by ChEMBL | Assay Description Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated... | ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Therapeutics Curated by ChEMBL | Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo... | J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Rattus norvegicus) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Inc. Curated by ChEMBL | Assay Description Inhibition of full length recombinant rat LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated f... | ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Mus musculus) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Inc. Curated by ChEMBL | Assay Description Inhibition of full length recombinant mouse LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated... | ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 3 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio... | Bioorg Med Chem Lett 28: 3113-3118 (2018) Article DOI: 10.1016/j.bmcl.2018.07.001 BindingDB Entry DOI: 10.7270/Q28P6366 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Therapeutics Curated by ChEMBL | Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 15 mins ... | J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 243 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Inc. Curated by ChEMBL | Assay Description Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated... | ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 3 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester Curated by ChEMBL | Assay Description Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr... | J Med Chem 63: 2308-2324 (2020) Article DOI: 10.1021/acs.jmedchem.9b01112 BindingDB Entry DOI: 10.7270/Q2J38X0T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 372 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester Curated by ChEMBL | Assay Description Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ... | J Med Chem 63: 2308-2324 (2020) Article DOI: 10.1021/acs.jmedchem.9b01112 BindingDB Entry DOI: 10.7270/Q2J38X0T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 396 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Inc. Curated by ChEMBL | Assay Description Inhibition of full length recombinant human LOXL2 expressed in CHO cells spiked into human whole blood assessed as reduction in H2O2 production using... | ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd Curated by ChEMBL | Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba... | J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Therapeutics Curated by ChEMBL | Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 15 mins ... | J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-lysine 6-oxidase (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Inc. Curated by ChEMBL | Assay Description Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f... | ACS Med Chem Lett 8: 423-427 (2017) Article DOI: 10.1021/acsmedchemlett.7b00014 BindingDB Entry DOI: 10.7270/Q2542QV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-lysine 6-oxidase (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmAkea Therapeutics Curated by ChEMBL | Assay Description Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll... | J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 665 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester Curated by ChEMBL | Assay Description Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ... | J Med Chem 63: 2308-2324 (2020) Article DOI: 10.1021/acs.jmedchem.9b01112 BindingDB Entry DOI: 10.7270/Q2J38X0T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ... | US Patent US10717733 (2020) BindingDB Entry DOI: 10.7270/Q29K4F8R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Oxidized low-density lipoprotein receptor 1 (Bovine) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ... | US Patent US10717733 (2020) BindingDB Entry DOI: 10.7270/Q29K4F8R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QC06PC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Oxidized low-density lipoprotein receptor 1 (Bovine) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QC06PC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-lysine 6-oxidase (Bos taurus) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd Curated by ChEMBL | Assay Description Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... | J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QC06PC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Mao-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QC06PC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida... | US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h... | US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h... | US Patent US10717733 (2020) BindingDB Entry DOI: 10.7270/Q29K4F8R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxidase, copper-c... | US Patent US10717733 (2020) BindingDB Entry DOI: 10.7270/Q29K4F8R | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester Curated by ChEMBL | Assay Description Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ... | J Med Chem 63: 2308-2324 (2020) Article DOI: 10.1021/acs.jmedchem.9b01112 BindingDB Entry DOI: 10.7270/Q2J38X0T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein-lysine 6-oxidase (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi... | Bioorg Med Chem Lett 28: 3113-3118 (2018) Article DOI: 10.1016/j.bmcl.2018.07.001 BindingDB Entry DOI: 10.7270/Q28P6366 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 4 (Homo sapiens) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human LOXL4 expressed in baculovirus infected insect cells using diaminopentane as substrate preincubated for 30 mins follo... | Bioorg Med Chem Lett 28: 3113-3118 (2018) Article DOI: 10.1016/j.bmcl.2018.07.001 BindingDB Entry DOI: 10.7270/Q28P6366 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Oxidized low-density lipoprotein receptor 1 (Bovine) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ... | US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lysyl oxidase homolog 2 (Homo sapiens (Human)) | BDBM50232678 (CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd. US Patent | Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ... | US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
