Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50056393'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50056393 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-14-18(22)17(21)13-16(19)20(25)27-12-11-23-7-9-24(10-8-23)15-5-3-2-4-6-15/h2-6,13-14H,7-12,22H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4C receptor isoform expressed in COS-7 cells				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50056393 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-14-18(22)17(21)13-16(19)20(25)27-12-11-23-7-9-24(10-8-23)15-5-3-2-4-6-15/h2-6,13-14H,7-12,22H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4E receptor isoform expressed in C6 glial cells incubated with 0.2 nM [3H]-GR-113,...				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50056393 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-14-18(22)17(21)13-16(19)20(25)27-12-11-23-7-9-24(10-8-23)15-5-3-2-4-6-15/h2-6,13-14H,7-12,22H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4A receptor isoform expressed in COS-7 cells				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50056393 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-14-18(22)17(21)13-16(19)20(25)27-12-11-23-7-9-24(10-8-23)15-5-3-2-4-6-15/h2-6,13-14H,7-12,22H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4D receptor isoform expressed in COS-7 cells				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50056393 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-14-18(22)17(21)13-16(19)20(25)27-12-11-23-7-9-24(10-8-23)15-5-3-2-4-6-15/h2-6,13-14H,7-12,22H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4B receptor isoform expressed in COS-7 cells				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50056393 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pheny...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24ClN3O3/c1-26-19-14-18(22)17(21)13-16(19)20(25)27-12-11-23-7-9-24(10-8-23)15-5-3-2-4-6-15/h2-6,13-14H,7-12,22H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-BIOCIS Curated by ChEMBL					Assay Description 5-hydroxytryptamine 4 receptor antagonist activity, concentration which gave 50% reduction of the 5-HT-induced contractions in the guinea pig ileum				J Med Chem 40: 608-21 (1997) Article DOI: 10.1021/jm960320m BindingDB Entry DOI: 10.7270/Q2T72J36
					More data for this Ligand-Target Pair