BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50327858'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
University of Oslo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
University of Oslo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranes				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4 receptor expressed in HEK293 cells				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Sus scrofa)	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a
Molecular NeuroImaging LLC Curated by ChEMBL					Assay Description Binding affinity to 5HT4 receptor in pig striatal membranes				Bioorg Med Chem Lett 23: 6243-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.097 BindingDB Entry DOI: 10.7270/Q2RJ4KZ2
Molecular NeuroImaging LLC Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Agonist activity at 5HT4 receptor expressed in HEK293/L9 cells by cAMP assay				J Med Chem 53: 7035-47 (2010) Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7
National Institute of Mental Health Curated by ChEMBL					More data for this Ligand-Target Pair