Found 6 hits for monomerid = 50327858 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 4 (5-HT4)
(Homo sapiens (Human)) | BDBM50327858
((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...)Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 | UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oslo
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001)
Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 4 (5-HT4)
(Homo sapiens (Human)) | BDBM50327858
((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...)Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 | UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oslo
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001)
Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP |
More data for this Ligand-Target Pair | |
HTR4
(GUINEA PIG) | BDBM50327858
((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...)Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health
Curated by ChEMBL
| Assay Description Displacement of [3H]GR113808 from 5HT4 receptor in guinea pig striatal membranes |
J Med Chem 53: 7035-47 (2010)
Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 4 (5-HT4)
(Homo sapiens (Human)) | BDBM50327858
((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...)Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 | UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health
Curated by ChEMBL
| Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4 receptor expressed in HEK293 cells |
J Med Chem 53: 7035-47 (2010)
Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7 |
More data for this Ligand-Target Pair | |
Serotonin 4 (5-HT4) receptor
(Sus scrofa) | BDBM50327858
((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...)Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a |
Molecular NeuroImaging LLC
Curated by ChEMBL
| Assay Description Binding affinity to 5HT4 receptor in pig striatal membranes |
Bioorg Med Chem Lett 23: 6243-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.09.097 BindingDB Entry DOI: 10.7270/Q2RJ4KZ2 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 4 (5-HT4)
(Homo sapiens (Human)) | BDBM50327858
((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...)Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 | UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
National Institute of Mental Health
Curated by ChEMBL
| Assay Description Agonist activity at 5HT4 receptor expressed in HEK293/L9 cells by cAMP assay |
J Med Chem 53: 7035-47 (2010)
Article DOI: 10.1021/jm100668r BindingDB Entry DOI: 10.7270/Q2BR8SD7 |
More data for this Ligand-Target Pair | |