Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM155395'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Rattus norvegicus (Rat))	BDBM155395 (US9006283, 5) Show SMILES COc1ccccc1NC(=O)C(=O)N1N=C(CC(C)C)CC1(O)C(F)(F)F |t:15| Show InChI InChI=1S/C17H20F3N3O4/c1-10(2)8-11-9-16(26,17(18,19)20)23(22-11)15(25)14(24)21-12-6-4-5-7-13(12)27-3/h4-7,10,26H,8-9H2,1-3H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	8.0	37
Acumen Pharmaceuticals, Inc. US Patent					Assay Description In this assay, assembly of Abeta 1-42 oligomer formation is monitored by FRET using N-terminal conjugates of fluorescein-Abeta 1-42 as both the donor...				US Patent US9006283 (2015) BindingDB Entry DOI: 10.7270/Q24T6H3Z
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