Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii) | BDBM50067865 (CHEMBL337603 | N*6*-(3,4-Dimethoxy-phenyl)-N*6*-me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.880 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibitory activity against dihydrofolate reductase (DHFR) from Toxoplasma gondii | J Med Chem 41: 4533-41 (1998) Article DOI: 10.1021/jm980206z BindingDB Entry DOI: 10.7270/Q2FX78KJ | |||||||||||
More data for this Ligand-Target Pair |