Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A' and Ligand = 'BDBM27353'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human))	BDBM27353 (2-(2-aminopyrimidin-4-yl)-6-(propan-2-yl)-1H,4H,5H...) Show SMILES CC(C)C1Cc2[nH]c(cc2C(=O)N1)-c1ccnc(N)n1 Show InChI InChI=1S/C14H17N5O/c1-7(2)10-6-11-8(13(20)18-10)5-12(17-11)9-3-4-16-14(15)19-9/h3-5,7,10,17H,6H2,1-2H3,(H,18,20)(H2,15,16,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	7.9	25
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX
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