Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A' and Ligand = 'BDBM27357'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human))	BDBM27357 (2-(2-aminopyrimidin-4-yl)-6-[(benzyloxy)methyl]-1H...) Show SMILES Nc1nccc(n1)-c1cc2c(CC(COCc3ccccc3)NC2=O)[nH]1 Show InChI InChI=1S/C19H19N5O2/c20-19-21-7-6-15(24-19)17-9-14-16(23-17)8-13(22-18(14)25)11-26-10-12-4-2-1-3-5-12/h1-7,9,13,23H,8,10-11H2,(H,22,25)(H2,20,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	7.9	25
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX
					More data for this Ligand-Target Pair