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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | US Patent | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
The University of North Carolina at Chapel Hill US Patent | Assay Description Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well... | US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(1B) dopamine receptor (RAT) | BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by PDSP Ki Database | Neuropsychopharmacology 20: 612-27 (1999) Article DOI: 10.1016/S0893-133X(98)00099-2 BindingDB Entry DOI: 10.7270/Q2ZP44NW | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Erlangen-N£rnberg Curated by ChEMBL | Assay Description Displacement of [3H]SCH23390 from human D5R expressed in HEK293T cell membranes | Bioorg Med Chem 25: 5613-5628 (2017) Article DOI: 10.1016/j.bmc.2017.08.037 BindingDB Entry DOI: 10.7270/Q2B56N7Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University Erlangen-Nuernberg Curated by ChEMBL | Assay Description Displacement of [3H]SCH23390 from human D5R expressed in HEK293T cell membranes by radioligand binding assay | J Med Chem 60: 4693-4713 (2017) Article DOI: 10.1021/acs.jmedchem.7b00363 BindingDB Entry DOI: 10.7270/Q2QC05NH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University Curated by PDSP Ki Database | Neuropsychopharmacology 28: 1400-11 (2003) Article DOI: 10.1038/sj.npp.1300203 BindingDB Entry DOI: 10.7270/Q2639N9T | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
