Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM185693'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185693 (UNC10099988 | US9156822, 34) Show SMILES Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185693 (UNC10099988 | US9156822, 34) Show SMILES Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	25	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185693 (UNC10099988 | US9156822, 34) Show SMILES Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	512	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185693 (UNC10099988 | US9156822, 34) Show SMILES Clc1cccc(N2CCN(CCCOc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1Cl Show InChI InChI=1S/C20H22Cl2N4O2/c21-15-3-1-4-18(19(15)22)26-10-8-25(9-11-26)7-2-12-28-14-5-6-16-17(13-14)24-20(27)23-16/h1,3-6,13H,2,7-12H2,(H2,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Intra-Cellular Therapies, Inc. US Patent									US Patent US8598119 (2013) BindingDB Entry DOI: 10.7270/Q28K77RC
					More data for this Ligand-Target Pair