Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50109019'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50109019 (Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chrom...) Show SMILES FC(F)(F)c1nc2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 Show InChI InChI=1S/C19H18F3N3O/c20-19(21,22)18-24-15-9-7-13-6-8-14(26-17(13)16(15)25-18)11-23-10-12-4-2-1-3-5-12/h1-5,7,9,14,23H,6,8,10-11H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Affinity of compound for D2 receptor in rat striatal membrane determined for agonist state (high affinity state, D2 High) [3H]quinpirole as radioliga...				Bioorg Med Chem Lett 12: 271-4 (2002) BindingDB Entry DOI: 10.7270/Q22J6CDZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50109019 (Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chrom...) Show SMILES FC(F)(F)c1nc2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 Show InChI InChI=1S/C19H18F3N3O/c20-19(21,22)18-24-15-9-7-13-6-8-14(26-17(13)16(15)25-18)11-23-10-12-4-2-1-3-5-12/h1-5,7,9,14,23H,6,8,10-11H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...				Bioorg Med Chem Lett 12: 271-4 (2002) BindingDB Entry DOI: 10.7270/Q22J6CDZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109019 (Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chrom...) Show SMILES FC(F)(F)c1nc2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 Show InChI InChI=1S/C19H18F3N3O/c20-19(21,22)18-24-15-9-7-13-6-8-14(26-17(13)16(15)25-18)11-23-10-12-4-2-1-3-5-12/h1-5,7,9,14,23H,6,8,10-11H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Laboratories Curated by ChEMBL					Assay Description Affinity for the Dopamine receptor D2S was determined using membranes from CHO cells labeled with [3H]spiperone				Bioorg Med Chem Lett 12: 271-4 (2002) BindingDB Entry DOI: 10.7270/Q22J6CDZ
					More data for this Ligand-Target Pair