Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A& M University Curated by ChEMBL | Assay Description Binding affinity to human cloned dopamine D4.4 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 3219-23 (2006) Article DOI: 10.1016/j.bmcl.2006.03.057 BindingDB Entry DOI: 10.7270/Q2571BM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation counting | Bioorg Med Chem 17: 1716-23 (2009) Article DOI: 10.1016/j.bmc.2008.12.054 BindingDB Entry DOI: 10.7270/Q2NG4QGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to human cloned dopamine D4 receptor | Bioorg Med Chem 16: 7291-301 (2008) Article DOI: 10.1016/j.bmc.2008.06.030 BindingDB Entry DOI: 10.7270/Q2ZP45XW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description Cataleptogenic effect against cloned human dopamine receptor D4 in male Sprague-Dawley rats in a bar test | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (RAT) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting | Bioorg Med Chem Lett 24: 4294-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50185473 (4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A & M University Curated by ChEMBL | Assay Description In vitro ability to inhibit the binding of [3H]-spiperone to cloned human dopamine receptor D4 using apomorphine induced climbing test in male Swiss ... | Bioorg Med Chem Lett 13: 3779-82 (2003) BindingDB Entry DOI: 10.7270/Q2BK1BQH | |||||||||||
More data for this Ligand-Target Pair |