Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM20724'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM20724 ((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)-c2ccc(cc2)C(=O)[C@@H]2CCC[C@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C27H26N2O5/c1-34-22-15-13-21(14-16-22)29-27(33)28-20-11-9-18(10-12-20)17-5-7-19(8-6-17)25(30)23-3-2-4-24(23)26(31)32/h5-16,23-24H,2-4H2,1H3,(H,31,32)(H2,28,29,33)/t23-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM20724 ((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...) Show SMILES COc1ccc(NC(=O)Nc2ccc(cc2)-c2ccc(cc2)C(=O)[C@@H]2CCC[C@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C27H26N2O5/c1-34-22-15-13-21(14-16-22)29-27(33)28-20-11-9-18(10-12-20)17-5-7-19(8-6-17)25(30)23-3-2-4-24(23)26(31)32/h5-16,23-24H,2-4H2,1H3,(H,31,32)(H2,28,29,33)/t23-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...				J Med Chem 51: 380-3 (2008) Article DOI: 10.1021/jm7013887 BindingDB Entry DOI: 10.7270/Q2KW5DB6
					More data for this Ligand-Target Pair