Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50438731'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50438731 (CHEMBL2414669) Show SMILES CC(C)(N)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCOc2ncnc(N)c2C1=O |r,wU:8.11,wD:5.4,(38.06,-43.71,;37.56,-42.25,;38.58,-41.09,;39.04,-42.64,;36.07,-41.95,;35.03,-43.12,;33.53,-42.83,;32.52,-43.97,;33.02,-45.46,;34.51,-45.72,;35.52,-44.57,;31.99,-46.63,;30.49,-46.33,;29.47,-47.49,;29.97,-48.96,;31.47,-49.23,;32.48,-48.08,;28.95,-50.12,;29.57,-51.55,;28.84,-52.91,;27.32,-53.2,;26.15,-52.17,;24.77,-52.9,;23.47,-52.08,;23.53,-50.52,;24.9,-49.81,;24.96,-48.26,;26.21,-50.64,;27.46,-49.72,;27.18,-48.2,)| Show InChI InChI=1S/C23H31N5O2/c1-23(2,25)13-15-3-5-16(6-4-15)17-7-9-18(10-8-17)28-11-12-30-21-19(22(28)29)20(24)26-14-27-21/h7-10,14-16H,3-6,11-13,25H2,1-2H3,(H2,24,26,27)/t15-,16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human full length DGAT-1 expressed in insect sf9 cells using [14C]decanoylCoA as substrate after 1.5 hrs by scintillation spectrometry				Bioorg Med Chem 21: 5081-97 (2013) Article DOI: 10.1016/j.bmc.2013.06.045 BindingDB Entry DOI: 10.7270/Q26111RG
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50438731 (CHEMBL2414669) Show SMILES CC(C)(N)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCOc2ncnc(N)c2C1=O |r,wU:8.11,wD:5.4,(38.06,-43.71,;37.56,-42.25,;38.58,-41.09,;39.04,-42.64,;36.07,-41.95,;35.03,-43.12,;33.53,-42.83,;32.52,-43.97,;33.02,-45.46,;34.51,-45.72,;35.52,-44.57,;31.99,-46.63,;30.49,-46.33,;29.47,-47.49,;29.97,-48.96,;31.47,-49.23,;32.48,-48.08,;28.95,-50.12,;29.57,-51.55,;28.84,-52.91,;27.32,-53.2,;26.15,-52.17,;24.77,-52.9,;23.47,-52.08,;23.53,-50.52,;24.9,-49.81,;24.96,-48.26,;26.21,-50.64,;27.46,-49.72,;27.18,-48.2,)| Show InChI InChI=1S/C23H31N5O2/c1-23(2,25)13-15-3-5-16(6-4-15)17-7-9-18(10-8-17)28-11-12-30-21-19(22(28)29)20(24)26-14-27-21/h7-10,14-16H,3-6,11-13,25H2,1-2H3,(H2,24,26,27)/t15-,16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of DGAT-1-mediated triglyceride synthesis in human HT-29 cells using [3H]-glycerol as substrate incubated for 1 hr prior to substrate addi...				Bioorg Med Chem 21: 5081-97 (2013) Article DOI: 10.1016/j.bmc.2013.06.045 BindingDB Entry DOI: 10.7270/Q26111RG
					More data for this Ligand-Target Pair