Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM50010928 (2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Alabama Curated by ChEMBL | Assay Description Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase. | J Med Chem 34: 222-7 (1991) BindingDB Entry DOI: 10.7270/Q2XD10N1 | |||||||||||
More data for this Ligand-Target Pair |