BindingDB PrimarySearch

Found 99 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50122654'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 13: 3617-22 (2003) BindingDB Entry DOI: 10.7270/Q24X576N
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human GnRH receptor expressed in CHO cells assessed as inhibition of GnRH-induced arachadonic acid release using [5,6,8,9,11,1...				J Med Chem 54: 4998-5012 (2011) Article DOI: 10.1021/jm200216q BindingDB Entry DOI: 10.7270/Q22N52MK
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition of arachidonic acid(AA) release from CHO cells in Human				J Med Chem 46: 113-24 (2002) Article DOI: 10.1021/jm020180i BindingDB Entry DOI: 10.7270/Q26W9BTR
Takeda Chemical Industries, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]leuprorelin from recombinant human GnRH receptor expressed in CHO cells after 60 mins by X-ray counter				J Med Chem 54: 4998-5012 (2011) Article DOI: 10.1021/jm200216q BindingDB Entry DOI: 10.7270/Q22N52MK
Takeda Pharmaceutical Company, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...				J Med Chem 46: 113-24 (2002) Article DOI: 10.1021/jm020180i BindingDB Entry DOI: 10.7270/Q26W9BTR
Takeda Chemical Industries, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at human GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
Neurocrine Biosciences, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L117A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y283F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186D				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189P				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K191E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290L				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR Y290L mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR A50T				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to LHRH receptor in monkey (chinese hamster ovary (CHO)...				J Med Chem 46: 113-24 (2002) Article DOI: 10.1021/jm020180i BindingDB Entry DOI: 10.7270/Q26W9BTR
Takeda Chemical Industries, Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T51A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Macaca mulatta)	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at monkey GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
Neurocrine Biosciences, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315D				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cells				J Med Chem 49: 6170-6 (2006) Article DOI: 10.1021/jm060580w BindingDB Entry DOI: 10.7270/Q20V8CFN
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F272L				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168I				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293N				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W291F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S124A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284F				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50122654 (1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T190K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

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