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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HTH-type transcriptional regulator ExsA' and Ligand = 'BDBM50378359'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HTH-type transcriptional regulator ExsA


(Pseudomonas aeruginosa)		BDBM50378359
PNG
(CHEMBL575963)
Show SMILES Cc1cc2nc(-c3ccc(NC(=O)\C=C\c4ccc(F)cc4)cc3)n(O)c2cc1[N+]([O-])=O
Show InChI InChI=1S/C23H17FN4O4/c1-14-12-19-21(13-20(14)28(31)32)27(30)23(26-19)16-5-9-18(10-6-16)25-22(29)11-4-15-2-7-17(24)8-3-15/h2-13,30H,1H3,(H,25,29)/b11-4+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.70E+3n/an/an/an/an/an/a



Paratek Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Pseudomonas aeruginosa ExsA binding to DNA

J Med Chem 52: 5626-34 (2009)


Article DOI: 10.1021/jm9006577
BindingDB Entry DOI: 10.7270/Q2XD12KZ
More data for this
Ligand-Target Pair