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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50127839'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50127839
PNG
(1-Methanesulfonyl-2-[4-(3-piperidin-1-yl-propoxy)-...)
Show SMILES CS(=O)(=O)n1c(cc2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1
Show InChI InChI=1S/C23H28N2O3S/c1-29(26,27)25-22-9-4-3-8-20(22)18-23(25)19-10-12-21(13-11-19)28-17-7-16-24-14-5-2-6-15-24/h3-4,8-13,18H,2,5-7,14-17H2,1H3
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 16n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development L. L. C.

Curated by ChEMBL


Assay Description
Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand

Bioorg Med Chem Lett 13: 1767-70 (2003)


BindingDB Entry DOI: 10.7270/Q21835V3
More data for this
Ligand-Target Pair