| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50127839 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_83646 |
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| Ki | 16±n/a nM |
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| Citation |  Chai, W; Breitenbucher, JG; Kwok, A; Li, X; Wong, V; Carruthers, NI; Lovenberg, TW; Mazur, C; Wilson, SJ; Axe, FU; Jones, TK Non-imidazole heterocyclic histamine H3 receptor antagonists. Bioorg Med Chem Lett13:1767-70 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | G-protein coupled receptor 97 | GPCR97 | HH3R | HISTAMINE H3 | HRH3 | HRH3_HUMAN | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48691.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. |
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| Residue: | 445 |
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| Sequence: | MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
RAFTKLLCPQKLKIQPHSSLEHCWK
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| BDBM50127839 |
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| n/a |
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| Name | BDBM50127839 |
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| Synonyms: | 1-Methanesulfonyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-1H-indole | CHEMBL51877 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N2O3S |
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| Mol. Mass. | 412.545 |
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| SMILES | CS(=O)(=O)n1c(cc2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1 |
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| Structure | 
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