BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Lysosomal alpha-glucosidase' and Ligand = 'BDBM50242271'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Competitive inhibition of rat intestinal maltase by Lineweaver-Burk plot analysis				J Med Chem 55: 10347-62 (2012) Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha-glucosidase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat small intestine maltase after 30 mins				Bioorg Med Chem Lett 21: 738-41 (2011) Article DOI: 10.1016/j.bmcl.2010.11.112 BindingDB Entry DOI: 10.7270/Q2D21XVS
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of maltase in human Caco-2 cell model system after 2 hrs				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal maltase using moltose as substrate				J Med Chem 55: 10347-62 (2012) Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 3298-301 (2014) Article DOI: 10.1016/j.bmcl.2014.06.001 BindingDB Entry DOI: 10.7270/Q2T43VRS
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal brush border membrane maltase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of lysosomal alpha-glucosidase by HPLC				J Med Chem 53: 689-98 (2010) Article DOI: 10.1021/jm901281m BindingDB Entry DOI: 10.7270/Q2M908TC
Leiden University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)