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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM397846'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))		BDBM397846
PNG
(US9994552, Compound 57)
Show SMILES COc1cccc(Cc2cnc(nc2)N2CCN(CC2)c2ncnc3cc(OC)c(OC)cc23)c1
Show InChI InChI=1S/C26H28N6O3/c1-33-20-6-4-5-18(12-20)11-19-15-27-26(28-16-19)32-9-7-31(8-10-32)25-21-13-23(34-2)24(35-3)14-22(21)29-17-30-25/h4-6,12-17H,7-11H2,1-3H3
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<1n/an/an/an/an/an/a



Duquesne University



Assay Description
Kit wild type assay: In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of ...

J Med Chem 52: 4892-902 (2009)


BindingDB Entry DOI: 10.7270/Q27M0B8Q
More data for this
Ligand-Target Pair