BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM397897'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM397897 (US9994552, Compound 108) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University					Assay Description Kit wild type assay: In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of ...				J Med Chem 52: 4892-902 (2009) BindingDB Entry DOI: 10.7270/Q27M0B8Q
Duquesne University					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM397897 (US9994552, Compound 108) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to KIT V816H mutant (unknown origin)				Bioorg Med Chem Lett 28: 1781-1784 (2018) Article DOI: 10.1016/j.bmcl.2018.04.030 BindingDB Entry DOI: 10.7270/Q21C20H6
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM397897 (US9994552, Compound 108) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to KIT V559D mutant (unknown origin)				Bioorg Med Chem Lett 28: 1781-1784 (2018) Article DOI: 10.1016/j.bmcl.2018.04.030 BindingDB Entry DOI: 10.7270/Q21C20H6
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM397897 (US9994552, Compound 108) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to KIT V559D/T670I mutant (unknown origin)				Bioorg Med Chem Lett 28: 1781-1784 (2018) Article DOI: 10.1016/j.bmcl.2018.04.030 BindingDB Entry DOI: 10.7270/Q21C20H6
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM397897 (US9994552, Compound 108) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to KIT (unknown origin)				Bioorg Med Chem Lett 28: 1781-1784 (2018) Article DOI: 10.1016/j.bmcl.2018.04.030 BindingDB Entry DOI: 10.7270/Q21C20H6
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM397897 (US9994552, Compound 108) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
University of the Pacific Curated by ChEMBL					Assay Description Binding affinity to KIT D816V mutant (unknown origin)				Bioorg Med Chem Lett 28: 1781-1784 (2018) Article DOI: 10.1016/j.bmcl.2018.04.030 BindingDB Entry DOI: 10.7270/Q21C20H6
University of the Pacific Curated by ChEMBL					More data for this Ligand-Target Pair