Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50017140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50017140 (CHEMBL3287062) Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C31H46N14O5/c1-17(46)42-25(13-19-15-37-16-41-19)29(50)44-22(8-4-10-38-30(33)34)27(48)43-23(9-5-11-39-31(35)36)28(49)45-24(26(32)47)12-18-14-40-21-7-3-2-6-20(18)21/h2-3,6-7,14-16,22-25,40H,4-5,8-13H2,1H3,(H2,32,47)(H,37,41)(H,42,46)(H,43,48)(H,44,50)(H,45,49)(H4,33,34,38)(H4,35,36,39)/t22-,23-,24-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity at wild type human melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assess...				J Med Chem 57: 4615-28 (2014) Article DOI: 10.1021/jm500064t BindingDB Entry DOI: 10.7270/Q2VQ347J
					More data for this Ligand-Target Pair