BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 7' and Ligand = 'BDBM50434069'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 7 (Homo sapiens (Human))	BDBM50434069 (CHEMBL2381339 \| US9676792, Compound 24) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	199	n/a	260	n/a	n/a	7.5	n/a
Dana-Farber Cancer Institute, Inc. US Patent					Assay Description Kinase activity was determined in an assay volume of 40 μl in kinase buffer (50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mM 2-mercaptoethanol) contai...				US Patent US9676792 (2017) BindingDB Entry DOI: 10.7270/Q2Z31WT7
Dana-Farber Cancer Institute, Inc. US Patent					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Homo sapiens (Human))	BDBM50434069 (CHEMBL2381339 \| US9676792, Compound 24) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of GST-tagged full length human ERK5 transfected in HEK293 cells assessed as inhibition of AP1 transcriptional activity after 24 hrs by du...				J Med Chem 56: 4413-21 (2013) Article DOI: 10.1021/jm4000837 BindingDB Entry DOI: 10.7270/Q2RF5WDZ
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair