Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50072215'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50072215 (1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...) Show SMILES CN1CCC=C(C1)c1nsnc1OCC#Cc1ccccc1 |c:4| Show InChI InChI=1S/C17H17N3OS/c1-20-11-5-10-15(13-20)16-17(19-22-18-16)21-12-6-9-14-7-3-2-4-8-14/h2-4,7-8,10H,5,11-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50072215 (1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...) Show SMILES CN1CCC=C(C1)c1nsnc1OCC#Cc1ccccc1 |c:4| Show InChI InChI=1S/C17H17N3OS/c1-20-11-5-10-15(13-20)16-17(19-22-18-16)21-12-6-9-14-7-3-2-4-8-14/h2-4,7-8,10H,5,11-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	241	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptor				J Med Chem 42: 1999-2006 (1999) Article DOI: 10.1021/jm9910019 BindingDB Entry DOI: 10.7270/Q2XD12BT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50072215 (1-Methyl-5-[4-(3-phenyl-prop-2-ynyloxy)-[1,2,5]thi...) Show SMILES CN1CCC=C(C1)c1nsnc1OCC#Cc1ccccc1 |c:4| Show InChI InChI=1S/C17H17N3OS/c1-20-11-5-10-15(13-20)16-17(19-22-18-16)21-12-6-9-14-7-3-2-4-8-14/h2-4,7-8,10H,5,11-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Stimulation of cAMP in CHO cells expressing human m2 receptor				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair