Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human)) | BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 9 | n/a | 170 | n/a | n/a | 7.4 | 4 |
Wyeth Research | Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test... | J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human)) | BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 9 | n/a | 16 | n/a | n/a | 7.4 | 4 |
Wyeth Research | Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ... | Bioorg Med Chem 17: 8086-92 (2009) Article DOI: 10.1016/j.bmc.2009.10.001 BindingDB Entry DOI: 10.7270/Q2VH5M54 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human)) | BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 10 | n/a | 16 | n/a | n/a | 7.4 | 4 |
Wyeth Research | Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test... | J Med Chem 49: 6151-4 (2006) Article DOI: 10.1021/jm0609566 BindingDB Entry DOI: 10.7270/Q20863KH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |