Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27671'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27671 (2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...) Show SMILES NC(=O)c1ccccc1OCCc1cccc(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C26H31N3O4/c27-24(30)22-10-3-4-11-23(22)33-17-12-19-6-5-9-21(18-19)26(32)29-15-13-28(14-16-29)25(31)20-7-1-2-8-20/h3-6,9-11,18,20H,1-2,7-8,12-17H2,(H2,27,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
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