Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50421157'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50421157 (CHEMBL2088608) Show SMILES Cn1c2ccccc2c2cc(\C=C\C(=O)c3cccc(NC(=O)C4CC4)c3)ccc12 Show InChI InChI=1S/C26H22N2O2/c1-28-23-8-3-2-7-21(23)22-15-17(9-13-24(22)28)10-14-25(29)19-5-4-6-20(16-19)27-26(30)18-11-12-18/h2-10,13-16,18H,11-12H2,1H3,(H,27,30)/b14-10+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-DOPA as substrate after 5 mins by UV-spectrophotometric analysis				Bioorg Med Chem 20: 5649-57 (2012) Article DOI: 10.1016/j.bmc.2012.07.001 BindingDB Entry DOI: 10.7270/Q24X5934
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50421157 (CHEMBL2088608) Show SMILES Cn1c2ccccc2c2cc(\C=C\C(=O)c3cccc(NC(=O)C4CC4)c3)ccc12 Show InChI InChI=1S/C26H22N2O2/c1-28-23-8-3-2-7-21(23)22-15-17(9-13-24(22)28)10-14-25(29)19-5-4-6-20(16-19)27-26(30)18-11-12-18/h2-10,13-16,18H,11-12H2,1H3,(H,27,30)/b14-10+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 5 mins by UV-spectrophotometric analysis				Bioorg Med Chem 20: 5649-57 (2012) Article DOI: 10.1016/j.bmc.2012.07.001 BindingDB Entry DOI: 10.7270/Q24X5934
					More data for this Ligand-Target Pair