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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily T member 1' and Ligand = 'BDBM50557676'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel subfamily T member 1


(Homo sapiens)
BDBM50557676
PNG
(CHEMBL4763955)
Show SMILES C[C@H](NC(=O)c1cc(nn1C)C(F)(F)F)c1nc(no1)-c1ccnc(c1)C1CC1 |r|
PDB

NCI pathway
Reactome pathway

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 16n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assay


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00675
BindingDB Entry DOI: 10.7270/Q2QF8XJ0
More data for this
Ligand-Target Pair
Potassium channel subfamily T member 1


(Mus musculus)
BDBM50557676
PNG
(CHEMBL4763955)
Show SMILES C[C@H](NC(=O)c1cc(nn1C)C(F)(F)F)c1nc(no1)-c1ccnc(c1)C1CC1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.14E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assay


Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00675
BindingDB Entry DOI: 10.7270/Q2QF8XJ0
More data for this
Ligand-Target Pair