Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM313571'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM313571 (N-(3-(2- (hydroxymethyl)- 2-methyl-3-oxo-5- (tetra...) Show SMILES Cc1ccc(NC(=O)c2cc(cnn2)C(F)(F)F)cc1-c1cc2OC(C)(CO)C(=O)Nc2c(c1)C1CCOCC1 Show InChI InChI=1S/C28H27F3N4O5/c1-15-3-4-19(33-25(37)22-11-18(13-32-35-22)28(29,30)31)12-20(15)17-9-21(16-5-7-39-8-6-16)24-23(10-17)40-27(2,14-36)26(38)34-24/h3-4,9-13,16,36H,5-8,14H2,1-2H3,(H,33,37)(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...				US Patent US10167279 (2019) BindingDB Entry DOI: 10.7270/Q2W0981V
					More data for this Ligand-Target Pair