Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM313657'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM313657 ((R)-N-(3-(2-(2,3- dihydroxypropoxy)-6- (tetrahydro...) Show SMILES Cc1ccc(NC(=O)c2cc(ccn2)C(F)(F)F)cc1-c1cc(OC[C@H](O)CO)nc(c1)C1CCOCC1 |r| Show InChI InChI=1S/C27H28F3N3O5/c1-16-2-3-20(32-26(36)24-12-19(4-7-31-24)27(28,29)30)13-22(16)18-10-23(17-5-8-37-9-6-17)33-25(11-18)38-15-21(35)14-34/h2-4,7,10-13,17,21,34-35H,5-6,8-9,14-15H2,1H3,(H,32,36)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...				US Patent US10167279 (2019) BindingDB Entry DOI: 10.7270/Q2W0981V
					More data for this Ligand-Target Pair