Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50070532'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50070532 (1-(5-Bromo-pyridin-2-yl)-3-[(1R,2R)-2-(3-ethoxy-2-...) Show SMILES CCOc1ccc(OC)c([C@H]2C[C@H]2NC(=O)Nc2ccc(Br)cn2)c1F Show InChI InChI=1S/C18H19BrFN3O3/c1-3-26-14-6-5-13(25-2)16(17(14)20)11-8-12(11)22-18(24)23-15-7-4-10(19)9-21-15/h4-7,9,11-12H,3,8H2,1-2H3,(H2,21,22,23,24)/t11-,12+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Medivir AB Curated by ChEMBL					Assay Description Inhibitory effect on wild type HIV- 1 reverse transcriptase using rCdG as template and dGTP as substrate.				Bioorg Med Chem Lett 8: 1511-6 (1999) BindingDB Entry DOI: 10.7270/Q2RR1XDZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50070532 (1-(5-Bromo-pyridin-2-yl)-3-[(1R,2R)-2-(3-ethoxy-2-...) Show SMILES CCOc1ccc(OC)c([C@H]2C[C@H]2NC(=O)Nc2ccc(Br)cn2)c1F Show InChI InChI=1S/C18H19BrFN3O3/c1-3-26-14-6-5-13(25-2)16(17(14)20)11-8-12(11)22-18(24)23-15-7-4-10(19)9-21-15/h4-7,9,11-12H,3,8H2,1-2H3,(H2,21,22,23,24)/t11-,12+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Medivir AB Curated by ChEMBL					Assay Description Inhibitory effect on recombinant HIV- 1 reverse transcriptase which has a mutation Tyr 181 to Cys 181 (clone 90)				Bioorg Med Chem Lett 8: 1511-6 (1999) BindingDB Entry DOI: 10.7270/Q2RR1XDZ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50070532 (1-(5-Bromo-pyridin-2-yl)-3-[(1R,2R)-2-(3-ethoxy-2-...) Show SMILES CCOc1ccc(OC)c([C@H]2C[C@H]2NC(=O)Nc2ccc(Br)cn2)c1F Show InChI InChI=1S/C18H19BrFN3O3/c1-3-26-14-6-5-13(25-2)16(17(14)20)11-8-12(11)22-18(24)23-15-7-4-10(19)9-21-15/h4-7,9,11-12H,3,8H2,1-2H3,(H2,21,22,23,24)/t11-,12+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Medivir AB Curated by ChEMBL					Assay Description Inhibitory effect on recombinant HIV- 1 reverse transcriptase which has a mutation Leu 100 to Ile 100 (clone 118)				Bioorg Med Chem Lett 8: 1511-6 (1999) BindingDB Entry DOI: 10.7270/Q2RR1XDZ
					More data for this Ligand-Target Pair