Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transcription factor Jun' and Ligand = 'BDBM50279699'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor Jun (Homo sapiens (Human))	BDBM50279699 (2-(4-Methyl-2-phenylamino-thiazol-5-yl)-3-o-tolyl-...) Show SMILES Cc1nc(Nc2ccccc2)sc1-c1nc2ccccc2c(=O)n1-c1ccccc1C |(-4.16,-12.94,;-3.02,-11.9,;-1.51,-12.22,;-.75,-10.89,;.79,-10.88,;1.56,-12.21,;.79,-13.55,;1.57,-14.87,;3.11,-14.87,;3.87,-13.52,;3.09,-12.2,;-1.78,-9.74,;-3.18,-10.37,;-4.51,-9.6,;-5.86,-10.38,;-7.2,-9.61,;-8.54,-10.38,;-9.87,-9.61,;-9.87,-8.06,;-8.54,-7.29,;-7.21,-8.06,;-5.87,-7.27,;-5.88,-5.73,;-4.52,-8.05,;-3.19,-7.27,;-1.86,-8.04,;-.52,-7.27,;-.53,-5.73,;-1.87,-4.96,;-3.2,-5.74,;-4.54,-4.98,)| Show InChI InChI=1S/C25H20N4OS/c1-16-10-6-9-15-21(16)29-23(28-20-14-8-7-13-19(20)24(29)30)22-17(2)26-25(31-22)27-18-11-4-3-5-12-18/h3-15H,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
B.V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL					Assay Description Inhibition of AP1 (unknown origin) expressed in HEK293 cells assessed as inhibition of TNFalpha-induced transcriptional activation treated 24 hrs bef...				Eur J Med Chem 44: 2184-9 (2009) Article DOI: 10.1016/j.ejmech.2008.10.031 BindingDB Entry DOI: 10.7270/Q25X28SV
					More data for this Ligand-Target Pair
Transcription factor Jun (Homo sapiens (Human))	BDBM50279699 (2-(4-Methyl-2-phenylamino-thiazol-5-yl)-3-o-tolyl-...) Show SMILES Cc1nc(Nc2ccccc2)sc1-c1nc2ccccc2c(=O)n1-c1ccccc1C |(-4.16,-12.94,;-3.02,-11.9,;-1.51,-12.22,;-.75,-10.89,;.79,-10.88,;1.56,-12.21,;.79,-13.55,;1.57,-14.87,;3.11,-14.87,;3.87,-13.52,;3.09,-12.2,;-1.78,-9.74,;-3.18,-10.37,;-4.51,-9.6,;-5.86,-10.38,;-7.2,-9.61,;-8.54,-10.38,;-9.87,-9.61,;-9.87,-8.06,;-8.54,-7.29,;-7.21,-8.06,;-5.87,-7.27,;-5.88,-5.73,;-4.52,-8.05,;-3.19,-7.27,;-1.86,-8.04,;-.52,-7.27,;-.53,-5.73,;-1.87,-4.96,;-3.2,-5.74,;-4.54,-4.98,)| Show InChI InChI=1S/C25H20N4OS/c1-16-10-6-9-15-21(16)29-23(28-20-14-8-7-13-19(20)24(29)30)22-17(2)26-25(31-22)27-18-11-4-3-5-12-18/h3-15H,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Inhibition of AP-1-mediated transcriptional activation in HEK293 cells by luciferase reporter gene assay				J Med Chem 57: 6930-48 (2014) Article DOI: 10.1021/jm5004733 BindingDB Entry DOI: 10.7270/Q2222WDT
					More data for this Ligand-Target Pair