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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM202112'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM202112
PNG
(US9233983, D-4)
Show SMILES CN1CCC(CC1)c1ccc(cc1)-c1cc2c(ncnc2[nH]1)-c1cccc(c1CO)-n1ccc2cc(ccc2c1=O)C1CC1
Show InChI InChI=1S/C37H35N5O2/c1-41-16-13-25(14-17-41)23-7-9-26(10-8-23)33-20-31-35(38-22-39-36(31)40-33)30-3-2-4-34(32(30)21-43)42-18-15-28-19-27(24-5-6-24)11-12-29(28)37(42)44/h2-4,7-12,15,18-20,22,24-25,43H,5-6,13-14,16-17,21H2,1H3,(H,38,39,40)
PDB
MMDB

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KEGG

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PC cid
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US Patent
n/an/a 3n/an/an/an/an/an/a



ADVINUS THERAPEUTICS LIMITED

US Patent


Assay Description
The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...


US Patent US9233983 (2016)


BindingDB Entry DOI: 10.7270/Q22J69PQ
More data for this
Ligand-Target Pair