Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50241408'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50241408 ((2S)-liquiritigenin | 7-HYDROXY-2-(4-HYDROXY-PHENY...) Show SMILES Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1 |r| Show InChI InChI=1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 mins				Bioorg Med Chem Lett 19: 5155-7 (2009) Article DOI: 10.1016/j.bmcl.2009.07.054 BindingDB Entry DOI: 10.7270/Q24X58R7
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50241408 ((2S)-liquiritigenin | 7-HYDROXY-2-(4-HYDROXY-PHENY...) Show SMILES Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1 |r| Show InChI InChI=1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B				J Nat Prod 69: 1572-6 (2006) Article DOI: 10.1021/np0601861 BindingDB Entry DOI: 10.7270/Q2B8591J
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50241408 ((2S)-liquiritigenin | 7-HYDROXY-2-(4-HYDROXY-PHENY...) Show SMILES Oc1ccc(cc1)[C@@H]1CC(=O)c2ccc(O)cc2O1 |r| Show InChI InChI=1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B assessed as p-nitorphenol production after 30 mins				Bioorg Med Chem 19: 3378-83 (2011) Article DOI: 10.1016/j.bmc.2011.04.037 BindingDB Entry DOI: 10.7270/Q2DF6RKT
					More data for this Ligand-Target Pair